ReviewFrontiers in immunology2026
Reinfection as a central constraint on tuberculosis vaccine development.
Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
1 author.
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Abstract
Tuberculosis (TB) vaccine development is hindered by the absence of validated correlates of protection, the low proportion of infected individuals who progress to disease, and the pervasive impact of reinfection in endemic settings. Although several candidates have advanced clinically, only M72/AS01E has demonstrated prevention of disease in adults. These limitations underscore the need to reassess both vaccine objectives and preclinical evaluation strategies. Epidemiological, immunological, and experimental evidence indicates that natural
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.