Evidence map›Paper›PMID 42093821›Full record

ArticleJournal of ophthalmology2026

Racial Variations in Retinal Oxygen Metabolic Biomarkers in Diabetic Retinopathy: A Pilot Study.

Katherine Tavasoli, Sophie Leahy, Norman P Blair, Farzan Abdolahi, Anthony E Felder, Mahnaz Shahidi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine TavasoliKeck School of Medicine, University of Southern California, Los Angeles, California, USA, usc.edu.ORCID https://orcid.org/0009-0006-4421-6390
Sophie LeahyDepartment of Ophthalmology, University of Southern California, Los Angeles, California, USA, usc.edu.ORCID https://orcid.org/0000-0002-9291-2116
Norman P BlairDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA, uic.edu.ORCID https://orcid.org/0000-0002-1482-2430
Farzan AbdolahiDepartment of Ophthalmology, University of Southern California, Los Angeles, California, USA, usc.edu.ORCID https://orcid.org/0000-0001-8794-487X
Anthony E FelderRichard and Loan Hill Department of Biomedical Engineering, University of Illinois Chicago, Chicago, Illinois, USA, uic.edu.ORCID https://orcid.org/0000-0002-4533-8369
Mahnaz ShahidiDepartment of Ophthalmology, University of Southern California, Los Angeles, California, USA, usc.edu.ORCID https://orcid.org/0000-0002-0156-1059

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
Imaging of Retinal Oxygen Metabolism in Diabetic RetinopathyR01EY030115 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHAHIDI, MAHNAZ · 2020 to 2024
$2.0M
NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY030115
6 · The paper itself

Abstract

Purpose: Previous studies have reported that race affects the prevalence and progression of diabetic retinopathy (DR). In this pilot study, we tested the hypothesis that there are associations between race and retinal oxygen metabolic biomarkers in subjects without diabetes or with diabetes at early stages of DR. Methods: A total of 104 subjects participated and were categorized into one of three diagnosis groups: nondiabetic (ND), diabetic without clinical DR (NDR), or diabetic with mild nonproliferative DR (mild NPDR). Subjects were also classified according to race as Asian (AS), African American (AA), Hispanic White (HW), or non-HW (NHW). Retinal oxygen metabolic biomarkers, namely, inner retinal oxygen delivery (DO Results: There were significant interactions of race and diagnosis group on retinal oxygen metabolic biomarkers. The effect of diagnosis group on MO Conclusion: The preliminary findings demonstrated associations of race with retinal oxygen metabolic biomarkers, underscoring the necessity for future studies in larger cohorts with the inclusion of potential confounding factors to establish normal baselines according to race that are needed for considering racial differences for clinical evaluation of DR.

Indexed as

diabetesoxygenraceretina

Identifiers

PMID42093821
PMCPMC13140414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.