Evidence map›Paper›PMID 42093809›Full record

ArticleCureus2026

A Rare Case of Stevens-Johnson Syndrome Secondary to Levofloxacin Administration: Presentation and Management.

Marios Chrysostomou, Nisarg Shah, Aparna Ravikumar, Fateh Khan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marios ChrysostomouInternal Medicine, York and Scarborough Teaching Hospitals NHS Foundation Trust, Scarborough, GBR.
Nisarg ShahInternal Medicine, York and Scarborough Teaching Hospitals NHS Foundation Trust, Scarborough, GBR.
Aparna RavikumarInternal Medicine, York and Scarborough Teaching Hospitals NHS Foundation Trust, Scarborough, GBR.
Fateh KhanRespiratory Medicine, York and Scarborough Teaching Hospitals NHS Foundation Trust, Scarborough, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stevens-Johnson syndrome (SJS) is a rare but life-threatening mucocutaneous reaction, most commonly triggered by medications and characterised by rapid progression, extensive mucosal involvement, and risk of long-term sequelae. We describe the case of a 74-year-old woman who developed severe SJS shortly after receiving levofloxacin for community-acquired pneumonia. Within days of antibiotic exposure, she experienced extensive mucocutaneous ulceration and profound ocular involvement, necessitating intensive multidisciplinary care. This case highlights the unpredictable nature of drug-associated SJS, the challenges of managing extensive ocular disease, and the importance of vigilance when prescribing widely used antibiotics. By underscoring the value of early identification and coordinated multidisciplinary care, it serves as a reminder that even familiar medications can provoke uncommon but severe reactions with the potential to cause life-changing consequences.

Indexed as

antibiotic therapycommunity-acquired pneumonia treatmentcutaneous adverse drug reactionfluoroquinolonesocular involvementstevens-johnson syndrometoxic epidermal necrolysis (ten)

Identifiers

PMID42093809
PMCPMC13143356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.