Evidence map›Paper›PMID 42093583›Full record

ArticleTheScientificWorldJournal2026

The Differences of Remineralization Potential of Bioactive Resin Infiltration and Conventional Resin Infiltration on Artificial Demineralized Enamel.

Kemporn Kitsahawong, Apa Juntavee, Niwut Juntavee, Chalita Suwannasuk, Chayapha Siriwatthanamethanon, Nattanicha Buddeesee, Rachata Somsub

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kemporn KitsahawongDepartment of Preventive Dentistry, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0000-9163-4188
Apa JuntaveeDepartment of Preventive Dentistry, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0002-1057-2972
Niwut JuntaveeDepartment of Prosthodontics, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0001-6229-6263
Chalita SuwannasukDivision of Biomaterials Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0004-4689-8685
Chayapha SiriwatthanamethanonDivision of Biomaterials Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0006-9511-8475
Nattanicha BuddeeseeDivision of Biomaterials Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0001-8332-2974
Rachata SomsubDivision of Biomaterials Research, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0009-5818-8206

Funding

Fundamental Fund 2568, Thailand Science Research and Innovation, Ministry of Higher Education, Science, Research and Innovation, Royal Thai Government 4777602
6 · The paper itself

Abstract

introductionManagement of demineralized enamel has focused on the use of materials for remineralization. This study compared the remineralization potential of bioactive remineralizing resin (2R) with conventional resin (CR) infiltration on demineralized enamel. MATERIAL AND

methodsSixty demineralized enamel premolars were generated, allocated for three groups for infiltration with 2R, CR, and no treatment (NT), and subjected to pH cycling. Samples were determined for microhardness of enamel at the levels 50-100-200-300 μm from the external surface. Polarized light microscopy (PLM) and energy dispersive spectroscopy were assessed for infiltration depth and calcium/phosphorus ratio (Ca/P). ANOVA and Fisher's test were analyzed for significant differences in microhardness and Ca/P among groups (α = 0.05).

results2R exhibited significantly higher hardness and Ca/P to demineralized enamel than CR and NT for every depth (p < 0.05), except for the hardness of 2R versus CR at 50 and 100 μm, and Ca/P of 2R-100 and 200 μm versus CR-50 μm. 2R showed significantly higher infiltration and remineralization to demineralized enamel than CR and NT. PLM denoted a greater decrease in depth of carious lesion for 2R, compared with CR, with no depth reduction for NT.

conclusion2R is capable of penetrating and enhancing the hardness of demineralized enamel more than CR, compared with NT. Increasing Ca/P upon infiltration with 2R over CR and NT denoted the capability of remineralization to carious lesions. A decrease in the depth of carious lesions was observed upon 2R application, more than CR and NT. CLINICAL RELEVANCE: 2R infiltration demonstrated an effective remineralization material for handling initial carious lesions in dental practice.

Indexed as

Dental EnamelResins, SyntheticTooth DemineralizationTooth RemineralizationCalciumHardnessHumansPhosphorusCalciumPhosphorusResins, Synthetic

Identifiers

PMID42093583
PMCPMC13150433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.