ArticlePediatrics international : official journal of the Japan Pediatric Society
Elective Initial Blood Testing for the Neurological Outcomes of Pediatric Out-of-Hospital Cardiac Arrests.
Article in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionPredictive blood testing for outcomes of out-of-hospital cardiac arrest (OHCA) remains unclear in childhood.
methodsWe retrospectively analyzed < 15 years old patients with OHCA who entered Kyushu University Hospital between 2006 and 2021. Pediatric Cerebral Performance Category Scale (PCPC) and ΔPCPC score (post-arrest PCPC 30 days minus pre-arrest value) classified them into intact survival (ΔPCPC = 0) or poor survival (ΔPCPC = 1-4), and death or brain-death (PCPC = 6). Initial laboratory data on admission were studied focusing on outcomes and time from detection of CA to emergency room (ED).
resultsEligible 115 patients included 38 (15 intact-, 23 poor-) survivors and 77 deaths. Serum transaminase, lactate dehydrogenase, and potassium levels were higher in death cases than survivors, but did not differentiate poor from intact survivors. Blood gas data showed better levels in intact survivors than others, but did not differentiate poor survivors from deaths. In 41 witnessed cases including 16 (8 intact-, 8 poor-) survivors, no one survived with > 40 min of time from detection of CA to ED. In 28 witnessed cases with < 40 min of time from CA to ED, no biochemical variables discriminated the three groups of patients, but three blood gas parameters (pH, HCO
conclusionsInitial blood gas data on admission provide valuable information for estimating the duration of CA before hospital arrival and reflect survivors' outcomes in pediatric OHCA patients.
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