Evidence map›Paper›PMID 42092977›Full record

ArticleTropical medicine and health2026

Nasal carriage and antimicrobial resistance of coagulase-negative staphylococci among male healthcare trainees in Southwestern Saudi Arabia: a cross-sectional study.

Ihab M Abdelrahim, Yahya Shabi, Abdulah J Alqahtani, Abdullah M Alkahtani, Martin Joseph, Mona Elfaki, Soliuman Mohamed, Mashoor A Alamir, Eissa Alfaifi, Maram Alhudiry and 3 more

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Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Ihab M AbdelrahimDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Yahya ShabiDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia. shabi.yahya@gmail.com.
Abdulah J AlqahtaniDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Abdullah M AlkahtaniCollege of Applied Medical Science, King Khalid University, Muhayil Asir, Saudi Arabia.
Martin JosephDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mona ElfakiDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Soliuman MohamedDepartment of Haematology and Immunohaematology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.
Mashoor A AlamirMedical City, King Khalid University, Abha, Saudi Arabia.
Eissa AlfaifiMedical City, King Khalid University, Abha, Saudi Arabia.
Maram AlhudiryMedical City, King Khalid University, Abha, Saudi Arabia.
Mohammed AsiriMedical City, King Khalid University, Abha, Saudi Arabia.
Saleh M Al-QahtaniDepartment of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mohamed E HamidDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.

Funding

Deanship of Scientific Research, King Khalid University RGP.2/557/46
6 · The paper itself

Abstract

backgroundCoagulase-negative staphylococci (CoNS) are increasingly recognized as clinically relevant colonizers in healthcare settings; however, their nasal carriage patterns and antimicrobial resistance profiles remain under-characterized, particularly among healthcare trainees. This study aimed to determine the prevalence, species distribution, clinical associations, and antimicrobial susceptibility patterns of CoNS among male healthcare trainees in Southwestern Saudi Arabia.

methodsA cross-sectional study was conducted involving 249 male healthcare trainees at King Khalid University. Nasal swabs were collected and cultured, with bacterial identification performed using the BD Phoenix™ M50 automated system. Antimicrobial susceptibility testing was conducted using disk diffusion in accordance with Clinical and Laboratory Standards Institute (CLSI) guidelines. Logistic regression was used to assess associations between colonization, clinical symptoms, and medical history.

resultsStaphylococcus epidermidis was the predominant species (64.3%). Recent antibiotic use was inversely associated with S. epidermidis carriage (OR 0.41; 95% CI 0.24-0.70) and positively associated with Staphylococcus cohnii subsp. cohnii carriage (OR 11.08; 95% CI 3.21-38.31). Staphylococcus warneri showed associations with halitosis (OR 416.25) and runny nose (OR 32.3); however, these estimates had extremely wide confidence intervals due to small sample sizes and should be interpreted as exploratory findings. Resistance profiles varied by species, with S. warneri exhibiting the highest resistance to methicillin markers (37.5%), while all CoNS isolates remained susceptible to vancomycin and linezolid.

conclusionHealthcare trainees harbor diverse CoNS species with distinct clinical and resistance profiles. The predominance of S. epidermidis alongside the presence of resistant non-epidermidis CoNS species, particularly S. warneri, highlights the clinical relevance of these organisms beyond their traditional classification as benign colonizers. These findings underscore the importance of considering CoNS in surveillance and antimicrobial stewardship efforts within clinical training environments.

Indexed as

Antimicrobial resistanceCoagulase-negative staphylococciHealthcare traineesNasal carriageSaudi ArabiaStaphylococcus epidermidisStaphylococcus warneri

Identifiers

PMID42092977
PMCPMC13214433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.