Evidence map›Paper›PMID 42092871›Full record

SynthesisBMC oral health2026

Efficacy and safety of diode laser in pulpotomy: a systematic review and meta-analysis.

Zi-Qi Cao, Nu-Nuo Pan, Fei-Fei Jia, Xiao-Mei Han, Ting Wei, Chao Zhang, Ling-Yun Xia, Min Mao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zi-Qi CaoShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Nu-Nuo PanShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Fei-Fei JiaShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Xiao-Mei HanShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Ting WeiShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Chao ZhangShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China. zhangchao0803@126.com.
Ling-Yun XiaShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China. xialingyun200810@163.com.
Min MaoShiyan Key Laboratory of Comprehensive Prevention and Treatment of Oral Cancer, Center of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China. 13972466005@139.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulpotomy is a commonly used approach for treating deep caries in primary teeth. In recent years, diode lasers have been explored the use in pulpotomy. This study systematically reviewed the clinical and radiographic efficacy of diode lasers in pulpotomy and evaluated their feasibility and safety as an alternative treatment modality.

methodsThis systematic review searched PubMed, Embase and the Cochrane Library for all published articles in the English language from inception to August 31, 2025. The medical subject headings (MeSH) terms and free-text keywords were used. The Cochrane collaboration risk assessment tool was used to evaluate the quality of the literature. Meta-analysis was performed using RevMan 5.4. Heterogeneity was evaluated using Cochran's Q test and the I

resultsThe results of this study showed that comparing with other treatments, no significant differences in clinical or radiographic success rates at every follow-up period (P > 0.05). However, diode lasers significantly decreased the occurrence of pathologic widening of the periodontal space (P < 0.05). Laser wavelength did not significantly influence the outcome (P > 0.05). When using zinc oxide eugenol (ZOE) as the pulp capping material, diode lasers lowered the incidence of pathological widening of the periodontal ligament space (P < 0.05). Sensitivity analyses confirmed that most results were consistent, although some subgroup outcomes were affected when individual studies were excluded. Funnel plot examination indicated no evidence of publication bias.

conclusionCompared with other methods, diode laser treatment demonstrated similar clinical and radiographic success rates and showed potential benefits in reducing the incidence of pathologic widening of periodontal space. Therefore, diode laser-assisted pulpotomy may be considered a viable alternative therapy.

trial registrationThe study was submitted to the Open Science Framework platform [ https://osf.io/rweuq/overview?view_only=fa297ad91199454581a03dedc1b3d4e0 ].

Indexed as

Lasers, SemiconductorPulpotomyHumansTreatment OutcomeZinc Oxide-Eugenol CementZinc Oxide-Eugenol CementDiode laserMeta-analysisPrimary teethPulpotomy

Identifiers

PMID42092871
PMCPMC13339851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.