SynthesisBMC psychiatry2026
A systematic review of the prevalence of fatigue in common mental disorders (mood disorders, anxiety disorders, personality disorders, and trauma and stressor related disorders).
Synthesis in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Less systematic decision-making during delay discounting, but not discounting rate, is robustly linked to psychopathology.Journal of psychopathology and clinical science · 2026Article
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Authors and funding
8 authors.
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Abstract
backgroundFatigue is a common symptom in the general population, as well as in several somatic conditions. Despite this, no review has yet examined the occurrence of fatigue across common mental disorders (CMD) such as mood disorders, anxiety disorders, personality disorders, and trauma and stressor related disorders. The objective of the review was to examine the prevalence of fatigue in patients with CMD, how fatigue when fatigue occurs in these populations, and it's relationshop with other outcomes.
methodWe searched in 2026 Medline, PsychInfo, and Embase for studies reporting on fatigue in CMD and conducted a manual search of the included references. Two reviewers independently selected papers and extracted data. Eligible studies were on patients with CMD without somatic illness, that employed a measure designed to assess fatigue. We conducted and reported the systematic review following the PRISMA statement. The evidence was synthesized according to whether it reports on the prevalence of fatigue, or provides data on the temporal occurrence of fatigue in the trajectory of the disorders.
resultsWe screened 7861 abstracts, and read full text on 393 papers and finally included 46 papers, of which 40 reported on prevalence. Most research concerned patients with mood disorders. Fatigue was found to be highly prevalent across CMD, with prevalences between 18% and 100%. Research suggests that fatigue can predict the onset of depression and that depression can predict the onset of fatigue. DISCUSSION: Fatigue is highly prevalent across patients with CMD and can therefore be regarded as a transdiagnostic symptom. A host of research suggests that fatigue in depression and anxiety can be explained by biological symptoms such as low-grade inflammation. Limitations includes high heterogeneity in the assessment of fatigue across included studies, and few instruments were validated for this population.
conclusionsThe symptom of fatigue was found to be prevalent across samples of patients with CMD, which highlights it as a possible transdiagnostic treatment target.
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