Evidence map›Paper›PMID 42092769›Full record

ArticleEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2026

Home-based physical exercice with additional cognitive training for improving mobility in older adults: a secondary analysis of the COVEPIC randomized controlled trial.

Emma Gabrielle Dupuy, Caroll-Ann Blanchette, Florent Besnier, Christine Gagnon, Thomas Vincent, Tudor Vrinceanu, Juliana Breton, Kathia Saillant, Josep Iglesies-Grau, Sylvie Belleville and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04635462 (The Cognitive and spOrt Virtual EPIC Training Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04635462 nacompletednot on this map

The Cognitive and spOrt Virtual EPIC Training Study: INVESTIGATING THE EFFECTS OF HOME-BASED EXERCISE AND COGNITIVE TRAINING

TypeinterventionalSponsorLouis BhererRan2020 to 2022Enrolled127ConditionsAgingArmsPhysical exercise training, Cognitive training
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Emma Gabrielle DupuyResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada. emma.dupuy@u-bourgogne.fr.
Caroll-Ann BlanchetteResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Florent BesnierResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Christine GagnonResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Thomas VincentResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Tudor VrinceanuResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Juliana BretonResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Kathia SaillantResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Josep Iglesies-GrauResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Sylvie BellevilleResearch center, Institut Universitaire de Gériatrie de Montréal, Montreal, Canada.
Martin JuneauResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Paolo VitaliMcGill Research Centre for Studies in Aging, Douglas Mental Health University Institute, Montreal, Canada.
Anil NigamResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Mathieu GaydaResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.
Louis BhererResearch center and Centre ÉPIC, Montreal Heart Institute, Montreal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHome-based physical exercise is an accessible strategy to help maintain physical functioning in adults over 50, but mobility gains may be limited without direct supervision. By improving cognitive processes involved in motor control, cognitive training may help enhance the effectiveness of home-based physical exercise in preventing age-related decline in mobility. This study compares the effects of a six-month home-based physical exercise, with or without cognitive training, on gait speed and balance.

methods127 community-dwelling adults aged 50-87 years (mean 65.20 ± 7.93; 76% women) were randomly assigned to (1) home-based, remotely monitored physical exercise alone (n = 64; 72% women) or (2) combined with cognitive training (n = 63; 81% women) for six months. The primary outcome was the change from baseline in usual gait speed, measured by the 4-meter walking test. Secondary outcomes included fast gait speed, balance (one-leg stance test), and lower-limb strength (five-time sit-to-stand test), all of which were assessed via videoconference at 3 and 6 months. Changes in outcomes were analyzed using adjusted mixed linear models with intervention group, time (ΔT0-T3, ΔT0-T6), and their interaction as fixed effects.

resultsChange in usual gait speed did not differ between groups. In contrast, the combined group showing greater improvements than the physical exercise alone group in fast gait speed (+ 0.07 m/s; F(1,199) = 6.24, p = 0.013, η

conclusionAdding cognitive training to home-based physical exercise may improve fast gait speed and balance in adults aged 50 and above. These findings support the interplay between sensorimotor and cognitive functions in older adults and suggest that combined physical and cognitive interventions could help prevent age-related mobility decline. CLINICAL TRIAL REGISTRATION ID: COVEPIC was retrospectively registered on November 19, 2020. CLINICAL TRIAL IDENTIFIER: NCT04635462. https://clinicaltrials.gov/ct2/show/record/NCT04635462?term=NCT04635462&draw=2&rank=1.

Indexed as

AgingBalanceCognitionGait SpeedMultidomain interventionPhysical ExerciseRemote Monitoring

Identifiers

PMID42092769
PMCPMC13330402

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.