Dynamic Control of Nucleic Acids Self-Assembly and Expression Using Photoswitches.

Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin

Abstract readReview

In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Noemí NogalDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0003-2731-2357

Hugo LaigleInstitut des Biomolécules Max Mousseron (IBMM), CNRS, ENSCM, Université de Montpellier, Montpellier, France.

Maxime MansyLaboratory For Chemistry of Novel Materials, Center of Innovation and Research in Materials and Polymers (CIRMAP), University of Mons, Mons, Belgium.

Sébastien UlrichInstitut des Biomolécules Max Mousseron (IBMM), CNRS, ENSCM, Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-6080-3345

Mathieu SurinLaboratory For Chemistry of Novel Materials, Center of Innovation and Research in Materials and Polymers (CIRMAP), University of Mons, Mons, Belgium.ORCID https://orcid.org/0000-0001-8950-3437

Funding

ANR ANR-23-CE07-0040-01Fund for Scientific Research F.R.S.-FNRS 30650939Fund for Scientific Research F.R.S.-FNRS U.G.018.18

6 · The paper itself

Abstract

Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science-where they can be used to engineer DNA origami-and biotechnologies, where they act as bioactive entities. It has therefore become of interest to develop chemical approaches enabling an external control over their function. In this line, photoswitches have attracted a strong interest since light is a benign stimulus which can be applied with spatio-temporal precision. In this review, we showcase the recent evolution in the design of photoswitches with improved performances, and highlight selected applications of their combination with nucleic acids.

Indexed as

DNANucleic AcidsDNA NanostructuresLightNucleic Acid ConformationPhotochemical ProcessesDNANucleic Acidsnucleic acidsphotocontrolphotoswitchesself‐assemblysupramolecular chemistry

Identifiers

PMID42092738

DOI10.1002/chem.71079

PMCPMC13485247

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.