Evidence map›Paper›PMID 42092180›Full record

ArticleScientific reports2026

Scalable production of monovalent streptavidin with high yield and purity.

Ian D Wadsworth, Komal Sethi, Sara Abu Jalboush, LeAnn Rogers, Thomas Hollis, Adam R Hall

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ian D WadsworthVirginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Komal SethiVirginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Sara Abu JalboushDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.
LeAnn RogersDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.
Thomas HollisDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.
Adam R HallVirginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA. Adam.Hall@wfusm.edu.

Funding

Molecular Detection of DNA Hydroxymethylation for Cancer ScreeningR21CA193067 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HALL, ADAM ROGER · 2015 to 2017
$649k
NIH HHS R21CA193067
6 · The paper itself

Abstract

The tetrameric protein streptavidin has found ubiquitous use in a wide variety of applications due to its ability to bind biotin molecules with remarkable affinity (K

Indexed as

StreptavidinBiotinEscherichia coliMaltose-Binding ProteinsRecombinant Fusion ProteinsRecombinant ProteinsSolubilityBiotinMaltose-Binding ProteinsRecombinant Fusion ProteinsRecombinant ProteinsStreptavidin

Identifiers

PMID42092180
PMCPMC13338456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.