Evidence map›Paper›PMID 42092165›Full record

ArticleNature plants2026

Root hair lifespan is antagonistically controlled by autophagy and programmed cell death.

Qiangnan Feng, Shihao Zhu, Xinchao Wang, Yujie Liu, Jierui Zhao, Yasin Dagdas, Moritz K Nowack

Abstract read
PubMed Publisher
In one paragraph

Article in Nature plants, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiangnan Feng *State Key Laboratory of Wheat Improvement, College of Life Sciences, Shandong Agricultural University, Tai'an, China. qiangnan.feng@sdau.edu.cn.ORCID http://orcid.org/0000-0002-8450-6134
Shihao Zhu *State Key Laboratory of Wheat Improvement, College of Life Sciences, Shandong Agricultural University, Tai'an, China.
Xinchao Wang *State Key Laboratory of Wheat Improvement, College of Life Sciences, Shandong Agricultural University, Tai'an, China.ORCID http://orcid.org/0009-0005-2644-0316
Yujie LiuState Key Laboratory of Wheat Improvement, College of Life Sciences, Shandong Agricultural University, Tai'an, China.
Jierui ZhaoGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.ORCID http://orcid.org/0000-0002-6690-4040
Yasin DagdasGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.ORCID http://orcid.org/0000-0002-9502-355X
Moritz K NowackDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium. moritz.nowack@psb.vib-ugent.be.ORCID http://orcid.org/0000-0001-8918-7577

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101043370EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) CoG EXECUT.ER 864952EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) StG PROCELLDEATH 639234Fonds Wetenschappelijk Onderzoek (Research Foundation Flanders) G002120NFonds Wetenschappelijk Onderzoek (Research Foundation Flanders) G002620NNational Natural Science Foundation of China (National Science Foundation of China) 32400293National Natural Science Foundation of China (National Science Foundation of China) 32541039
6 · The paper itself

Abstract

Root hairs are tubular tip-growing extensions of root epidermal cells that enhance root surface area for water and nutrient acquisition. While the mechanisms governing root hair fate, polarity and tip growth are well understood, the regulation of root hair longevity remains largely unknown. Here we show that root hair cells employ high levels of autophagy to maximize their lifespan in Arabidopsis thaliana. Loss-of-function mutations in the genes encoding the autophagy regulators ATG2, ATG5 or ATG7 induce a premature, cell-autonomous cell death program. This cell death is activated via a gene regulatory network promoted by the NAC transcription factors ANAC046 and ANAC087. Our findings uncover an antagonistic relationship between autophagy and senescence-controlled programmed cell death in root hair lifespan regulation, with potential implications for optimizing plant nutrient and water uptake in crop breeding.

Indexed as

ApoptosisArabidopsisAutophagyPlant RootsArabidopsis ProteinsGene Expression Regulation, PlantArabidopsis Proteins

Identifiers

PMID42092165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.