ArticleScientific reports2026
Genetic susceptibility and gene-environment interactions in gastric cancer among ethnic populations of Northeast India.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Northeast India has a high burden of gastric cancer, but the factors driving this elevated risk remain poorly understood. This study examined genetic polymorphisms, germline mutations, and lifestyle factors contributing to gastric cancer risk in populations from Nagaland and Tripura. We conducted a case-control study of 190 gastric cancer patients recruited at the hospitals and 317 healthy community controls, integrating PCR-based genotyping of GSTM1, GSTT1, CYP2E1, TLR2, TLR4, TNF-α, and IL-10 with detailed assessment of lifestyle, diet, and Helicobacter pylori infection, alongside ARMS
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