Evidence map›Paper›PMID 42091970›Full record

ArticleScientific reports2026

Genetic susceptibility and gene-environment interactions in gastric cancer among ethnic populations of Northeast India.

Kangjam Rekha Devi, Debdutta Mukherjee, Sanjib Phukan, Mandakini Gogoi, Gautam Majumdar, V Khamo, Kanwar Narain

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kangjam Rekha DeviScientist-G, ICMR-RMRC, Dibrugarh, Assam, India. krekha75@yahoo.co.in.
Debdutta MukherjeeICMR-RMRC, Dibrugarh, Assam, India.
Sanjib PhukanICMR-RMRC, Dibrugarh, Assam, India.
Mandakini GogoiProject Scientist -II, ICMR-RMRC, Dibrugarh, Assam, India.
Gautam MajumdarFormer medical superintendent of the Regional Cancer Centre, Agartala, India.
V KhamoNaga Hospital Authority, Kohima, Nagaland, India.
Kanwar NarainFormer Director, ICMR-RMRC, Dibrugarh, Assam, India.

Funding

Indian Council of Medical Research 79/02/RMRC/NE/2014, NCD-III
6 · The paper itself

Abstract

Northeast India has a high burden of gastric cancer, but the factors driving this elevated risk remain poorly understood. This study examined genetic polymorphisms, germline mutations, and lifestyle factors contributing to gastric cancer risk in populations from Nagaland and Tripura. We conducted a case-control study of 190 gastric cancer patients recruited at the hospitals and 317 healthy community controls, integrating PCR-based genotyping of GSTM1, GSTT1, CYP2E1, TLR2, TLR4, TNF-α, and IL-10 with detailed assessment of lifestyle, diet, and Helicobacter pylori infection, alongside ARMS

Indexed as

EthnicityGene-Environment InteractionGenetic Predisposition to DiseaseStomach NeoplasmsAdultAgedCase-Control StudiesFemaleGenotypeGerm-Line MutationGlutathione TransferaseHelicobacter InfectionsHumansIndiaMaleMiddle AgedGlutathione TransferaseBetel nut chewingGastric cancerGene-environment interactionGenetic polymorphismsGermline mutationsNortheast IndiaTP53Wnt signalling pathway

Identifiers

PMID42091970
PMCPMC13338060

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.