ArticleScientific reports2026
Nano-enabled Control of A. flavus and F. proliferatum: inhibition of fungal growth and mycotoxin biosynthesis by zinc oxide nanoparticles.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Recently, zinc oxide nanoparticles (ZnO-NPs) have been proposed as more sustainable substitutes for chemical fungicides; however, their potential in fungicidal and mycotoxin biosynthesis control in food-related pathogens is still under research. In this study, we synthesized and characterized ZnO-NPs with a high degree of crystallinity and antifungal and antimycotoxigenic properties against two significant toxigenic fungi, Aspergillus flavus f10 and Fusarium proliferatum f30, by using a combination of microwave-assisted combustion. X-ray diffraction (XRD) and FTIR analyses confirmed the formation of a hexagonal wurtzite phase, while TEM imaging revealed rod-like ZnO nanostructures with diameters of approximately 70-90 nm and lengths extending up to approximately 700 nm. ZnO-NPs demonstrated high concentration-dependent fungicidal behavior; 150 ppm decreased the growth of A. flavus and F. proliferatum by 75 and 97%, respectively whereas bulk zinc sulfate had no effect. SEM revealed severe morphological damage, such as hyphal shrinkage, disturbed sporulation, and outgrowths. ZnO-NPs nearly completely inhibited aflatoxin biosynthesis (reduced AFB
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