Evidence map›Paper›PMID 42091832›Full record

ArticleCognitive, affective & behavioral neuroscience2026

Understanding loss aversion by using tDCS stimulation on DLPFC and multiple ERP measures: A tDCS-EEG study.

Jia Jin, Lu Dai, Zhongfeng Wang, Qin Xiao, Ailian Wang

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In one paragraph

Article in Cognitive, affective & behavioral neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jia JinKey Laboratory of Brain-Machine Intelligence for Information Behavior (Ministry of Education and Shanghai), School of Business and Management, Shanghai International Studies University, Shanghai, China.
Lu DaiKey Laboratory of Brain-Machine Intelligence for Information Behavior (Ministry of Education and Shanghai), School of Business and Management, Shanghai International Studies University, Shanghai, China.
Zhongfeng WangKey Laboratory of Brain-Machine Intelligence for Information Behavior (Ministry of Education and Shanghai), School of Business and Management, Shanghai International Studies University, Shanghai, China.
Qin XiaoKey Laboratory of Brain-Machine Intelligence for Information Behavior (Ministry of Education and Shanghai), School of Business and Management, Shanghai International Studies University, Shanghai, China.
Ailian WangSchool of Management, Shanghai University of International Business and Economics, 1900 Wenxiang Road, Songjiang District, Shanghai, 201620, China. alwang163@163.com.

Funding

National Nature Science Foundation of China 72271166Shanghai Key Laboratory of Brain-Machine Intelligence for Information Behavior 22dz2261100
6 · The paper itself

Abstract

Loss aversion is a crucial aspect of risky decision-making; yet its neural underpinnings remain unclear, particularly regarding the functional relationship between neural activity and behavior. This study employed bihemispheric DLPFC transcranial direct current stimulation (tDCS) and electroencephalogram (EEG) to deeply understand the neural mechanism of loss aversion from three aspects: 1) functional relationship of dorsolateral prefrontal cortex (DLPFC) on loss aversion; 2) comprehensive neural basis of loss aversion; 3) neural evidence of functional effect of DLPFC on loss aversion. Twenty-five healthy subjects underwent three stimulations, i.e., right anodal/left cathodal (right stimulation), left anodal/right cathodal (left stimulation), and sham stimulation targeted bilateral DLPFC on separate days with 7- to 14-day intervals. Participants performed a mixed gamble task poststimulation while EEG was recorded. Behaviorally, right stimulation reduced acceptance rate and increased loss aversion coefficients compared with sham and left stimulation. Moreover, both average and single-trial ERP analysis revealed enhanced feedback-related negativity difference (d-FRN) deflections following right stimulation, whereas no significant error-related negativity (ERN) effect was found. These findings suggested that right DLPFC is a key region driving loss aversion by increasing sensitivity to losses and modulating negative emotional responses.

Indexed as

Decision MakingDorsolateral Prefrontal CortexEvoked PotentialsPrefrontal CortexRisk-TakingTranscranial Direct Current StimulationAdultElectroencephalographyFemaleFunctional LateralityHumansMaleYoung AdultDorsolateral prefrontal cortexEvent-related potentialFeedback-related negativityLoss aversionTranscranial direct current stimulation

Identifiers

PMID42091832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.