Evidence map›Paper›PMID 42091500›Full record

ArticleThe Journal of veterinary medical science2026

Comparison of serum paraoxonase 1, butyrylcholinesterase, and carboxylesterase activities among dogs, cats, micro-mini pigs, and goats.

Seiko Doi, Yutaka Kobayashi, Satoshi Takashima, Wataru Ide, Yusuke Murahata, Masato Yayota, Masaki Takasu, Yukiko Sassa-O'Brien, Sanae Shibata

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seiko DoiJoint Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
Yutaka KobayashiJoint Department of Veterinary Medicine, Faculty of Applied Biological Science, Gifu University, Gifu, Japan.
Satoshi TakashimaJoint Department of Veterinary Medicine, Faculty of Applied Biological Science, Gifu University, Gifu, Japan.
Wataru IdeJoint Graduate School of Veterinary Sciences, Tottori University, Tottori, Japan.
Yusuke MurahataJoint Graduate School of Veterinary Sciences, Tottori University, Tottori, Japan.
Masato YayotaFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Masaki TakasuJoint Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
Yukiko Sassa-O'BrienLaboratory of Veterinary Infectious Disease, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Sanae ShibataJoint Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum nonspecific esterases, including paraoxonase 1 (PON1), butyrylcholinesterase (BChE), and carboxylesterase (CES), may influence the hydrolysis of some ester-containing drugs. However, data on these enzymes across animal species remain limited. This study compared serum PON1, BChE, and CES activities among dogs (n=6), cats (n=6), micro-mini pigs (n=6), and goats (n=8) using identical assay systems. Serum samples were analyzed using established colorimetric or fluorescent assays, and interspecies differences were evaluated using the Steel-Dwass test. PON1 activity was highest in goats, BChE activity was highest in dogs, and CES activity was highest in cats. These findings demonstrate distinct interspecies profiles of serum nonspecific esterase activities and provide baseline data for future studies investigating species differences in the metabolism of ester-containing compounds.

Indexed as

AryldialkylphosphataseButyrylcholinesteraseCarboxylesteraseGoatsAnimalsCatsDogsSpecies SpecificitySwineAryldialkylphosphataseButyrylcholinesteraseCarboxylesterasebutyrylcholinesterasecarboxylesteraseesterase activityparaoxonase 1species differences

Identifiers

PMID42091500
PMCPMC13369658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.