Evidence map›Paper›PMID 42091009›Full record

ArticleThe International journal on drug policy2026

Family-centered interventions for people with substance use disorders in low-and middle-income country settings: a scoping review.

Ashley Sharma, Carol Mita, Kennedy Dozier, Roshni Singh, Anand Chukka, Ramya Ramadas, Sonia Taneja, Abigail Batchelder, Sarah M Bagley, Aishwarya Thakur and 7 more

Abstract readScoping Review
In one paragraph

Article in The International journal on drug policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ashley SharmaRobert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.
Carol MitaCountway Library, Harvard Medical School, Boston, MA, USA.
Kennedy DozierHarvard School of Public Health, Boston, MA, USA.
Roshni SinghBoston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Anand ChukkaIcahn School of Medicine at Mount Sinai, New York City, NY, USA.
Ramya RamadasDivision of General Pediatrics, University of California at San Francisco School of Medicine, San Francisco, CA, USA.
Sonia TanejaBoston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Division of General Pediatrics, Boston Medical Center, Boston, MA, USA.
Abigail BatchelderBoston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Department of Psychiatry, Boston Medical Center, Boston, MA, USA.
Sarah M BagleyBoston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Division of General Pediatrics, Boston Medical Center, Boston, MA, USA; Department of Psychiatry, Boston Medical Center, Boston, MA, USA.
Aishwarya ThakurDivisions of General Pediatrics and Community Health, Adolescent and Young Adult Medicine, Children's National Medical Center, Washington D.C., USA; George Washington University School of Medicine and Health Sciences, Washington D.C., USA.
Matthew C SullivanBehavioral Medicine Program, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Satish Kumar SkYR Gaitonde Medical, Educational and Research Foundation, Chennai, Tamil Nadu, India.
Sunil S SolomonDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kenneth H MayerHarvard Medical School, Boston, MA, USA; Fenway Institute, Boston, MA, USA; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Conall O'CleirighBehavioral Medicine Program, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Areej HassanHarvard Medical School, Boston, MA, USA; Division of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, MA, USA.
Lakshmi GanapathiSection of General Internal Medicine, Department of Medicine, Boston Medical Center, USA; Harvard Medical School, Boston, MA, USA; Division of Pediatric Infectious Diseases and Global Health, Massachusetts General Hospital, Boston, MA, USA. Electronic address: lganapathi@mgh.harvard.edu.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Yuva Sath (Youth Together): A peer-led intervention to support substance use treatment engagement and HIV prevention among young people who inject drugsK23DA057151 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Lakshmi Ganapathi · 2023 to 2026
$777k
NIDA NIH HHS 1K24DA062568-01NIDA NIH HHS K23 DA057151NIH HHS P30AI060354
6 · The paper itself

Abstract

backgroundSubstance use disorders (SUD) present a significant global health challenge, impacting people who use drugs (PWUD) and their families. While family-centered interventions have shown positive outcomes in high-income countries, their application in low-and middle-income countries (LMICs) remains unexplored. This scoping review sought to synthesize existing research evaluating family-centered interventions for PWUD in LMICs.

methodsA comprehensive search was conducted across 6 databases. From 4838 titles and abstracts initially screened, 101 full texts were examined for eligibility. Data was extracted from 20 studies (14 quantitative, 3 qualitative, and 3 mixed method). For qualitative studies, a codebook was developed, and two coders applied thematic analysis principles to identify key themes.

resultsFamily-centered interventions were heterogenous in treatment approaches, interventionist training, and duration. Findings revealed improvements in SUD knowledge and outcomes (e.g., increased smoking abstinence, decreased alcohol use and relapse rates). Psychosocial outcomes included improved quality of life, stronger family support, improved communication, and problem-solving skills, as well as reduced depressive symptoms, contributing to PWUD emotional well-being. Qualitative studies corroborated these findings and highlighted multi-level implementation barriers including logistical challenges (transport barriers, competing responsibilities), financial insecurity, mistrust in services, and limited provider capacity.

conclusionsFamily-centered interventions show promise in improving substance use and psychosocial outcomes among PWUD in LMICs. However, further research is needed to address challenges in effective implementation including ameliorating barriers to sustained engagement and support for long-term recovery to ensure durable effectiveness.

Indexed as

Substance-Related DisordersDeveloping CountriesFamily SupportHumansQuality of LifeResource-Limited SettingsAddiction treatmentBehavioral health interventionsDrug and alcohol useFamily-centered interventionsLow-and middle-income countriesParental supportSubstance use

Identifiers

PMID42091009
PMCPMC13309164

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.