ArticleRevista medica del Instituto Mexicano del Seguro Social2026
[Cost-effectiveness of the Lose Weight, Gain Life program].
Article in Revista medica del Instituto Mexicano del Seguro Social, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The Pierde Kilos, Gana Vida program (Lose Weight, Gain Life, LWGLP) promotes the development of skills for adopting healthy lifestyle habits among the population of the Mexican Institute for Social Security (IMSS). The cost-effectiveness analysis (CEA) aims to evaluate the potential benefit of an intervention. Objective: To assess the real-world cost-effectiveness of the LWGLP. Material and methods: A historical, longitudinal, retrospective cohort study was conducted, which included patients with diagnosis of overweight or obesity enrolled in the LWGLP, and they were compared with those receiving conventional treatment (CT). Patients enrolled in the program who did not complete it were excluded. A cost-effectiveness ratio was calculated, and the cost per kilogram of weight loss was estimated for both groups. Results: A total of 31 patients from the LWGLP group and 31 from the CT group were included. The LWGLP group had an average weight loss of 4.2 kg compared to 0.4 kg in the CT group (p < 0.001). In the CEA, the LWGLP group lost a total of 109 kg, with a cost per kilogram loss of $1678.71 MXN (IQR 1221.83-4312.35). The CT group lost 19 kg, resulting in a cost per kilogram loss of $3701.18 MXN (IQR 2,176-6,452). The resulting cost-effectiveness index (CEI) was approximately $355.20 MXN additional per kilogram loss through the LWGLP. Conclusions: The LWGLP is effective in reducing weight, with a CEI of $355.20 MXN in additional cost per kilogram loss through the program.
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