ArticleProceedings of the National Academy of Sciences of the United States of America2026
3D epithelial cell topology tunes signaling range to promote precise patterning.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- 3D epithelial cell topology tunes signaling range to promote precise patterning.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- easytrack: A napari plugin for automated parameter tuning in cell tracking.microPublication biology · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
Cell behaviors in multicellular organisms are coordinated via both diffusible molecules and by signals based on direct cell-cell contacts. The mode of cell communication used influences the signaling range. In many developing epithelia, contact-based Notch-Delta lateral inhibition signaling is used to pattern cell fates. While previous work revealed that cells can use protrusions to extend the range of Notch-Delta signaling to alter these patterns, this is not a general feature of epithelia. In addition, it is not known how the complex three-dimensional (3D) shapes of epithelial cells influence cell communication. In exploring this question, we show that epithelial cells at the
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