Evidence map›Paper›PMID 42090115›Full record

ArticleJournal of endocrinological investigation2026

Comparative analysis of PTH Washout and 99mTc-MIBI SPECT/CT in presurgical localization for patients with primary hyperparathyroidism.

Maja Cieślewicz, Ewelina Szczepanek-Parulska, Agnieszka Witowska, Dorota Filipowicz, Ariadna Zybek-Kocik, Rafał Czepczyński, Marek Ruchała

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maja CieślewiczDepartment of Endocrinology, Metabolism and Internal Diseases, Doctoral School, Poznan University of Medical Sciences, Przybyszewskiego Street 49, 60-355, Poznań, Poland. maja.cieslewicz@usk.poznan.pl.ORCID http://orcid.org/0000-0003-3425-7835
Ewelina Szczepanek-ParulskaDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0000-0003-3661-3274
Agnieszka WitowskaDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0009-0006-3203-8216
Dorota FilipowiczDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0000-0002-2205-4558
Ariadna Zybek-KocikDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0000-0001-6019-217X
Rafał CzepczyńskiDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0000-0003-0684-1647
Marek RuchałaDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland.ORCID http://orcid.org/0000-0002-6296-7220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur study aimed to evaluate the performance and concordance of parathyroid hormone wash-out (PTHw) and

methodsThis was a real-life, retrospective study involving 125 participants, who underwent ultrasound-guided fine needle aspiration biopsy with PTHw determined by electrochemiluminescence (Elecsys analyser) and subtraction scintigraphy together with SPECT/CT images.

resultsPTHw was positive in 84.8% and MIBI in 84.0% of cases, with concordant findings in 73.6% of patients. In MIBI-negative cases, PTHw accurately localized PA in 70.0%, while MIBI identified lesions in 68.4% of PTHw-negative cases. Larger lesions were associated with improved performance for both techniques, although a significant size-dependent effect (≥10 mm) was observed only for MIBI (χ

conclusionOur findings reinforce the complementary role of ultrasound-guided parathyroid hormone washout and

Indexed as

Hyperparathyroidism, PrimaryParathyroid GlandsParathyroid HormoneParathyroid NeoplasmsSingle Photon Emission Computed Tomography Computed TomographyTechnetium Tc 99m SestamibiAdultAgedBiopsy, Fine-NeedleFemaleHumansMaleMiddle AgedPreoperative CareRadiopharmaceuticalsRetrospective StudiesParathyroid HormoneRadiopharmaceuticalsTechnetium Tc 99m SestamibiFine-needle aspirationHyperparathyroidismParathyroid hormoneParathyroid neoplasmsTechnetium Tc 99m sestamibi

Identifiers

PMID42090115
PMCPMC13486070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.