Evidence map›Paper›PMID 42090106›Full record

ArticleJapanese journal of radiology2026

Regional disparities in pediatric radiotherapy utilization in Japan: analysis of a nationwide database.

Takahiro Aoyama, Yutaro Koide, Tomoki Kitagawa, Ryoma Tomoda, Shingo Hashimoto, Hiroyuki Tachibana, Takeshi Kodaira

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Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Takahiro AoyamaDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan. aoyamat@aichi-cc.jp.ORCID http://orcid.org/0000-0002-8423-6509
Yutaro KoideDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.
Tomoki KitagawaDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.
Ryoma TomodaDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.
Shingo HashimotoDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.
Hiroyuki TachibanaDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.
Takeshi KodairaDepartment of Radiation Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa- Ku, Nagoya, Aichi, 464-8681, Japan.

Funding

Children's Cancer Association of Japan CCAJ2024
6 · The paper itself

Abstract

backgroundPediatric radiotherapy (RT) plays a key role in childhood cancer care, yet regional disparities in its utilization and delivery persist. We aimed to quantify prefecture-level disparities in pediatric RT utilization and examine associations with workforce and facility factors. PROCEDURE: Using the Ministry of Health, Labour and Welfare National Database Open Data, we extracted counts of pediatric RT add-on claims (fractions) for fiscal year 2023. Utilization was calculated as claims per 100,000 children (< 15 years). Explanatory variables were the number of board-certified pediatricians and the presence of a designated pediatric cancer hub hospital in each prefecture. We conducted Pearson/Spearman correlation analyses and Welch's t-test, reporting Cohen's d. Supplementary analyses summarized prefecture-level distributions and 5-year trends (2019-2023).

resultsThe national mean utilization was 58.7 fractions per 100,000 children (range, 0.0-161.0), with marked inter-prefectural variability. Pediatrician numbers strongly correlated with claim counts (r = 0.94, p < 0.001) but not with claims per 100,000 children (r = 0.18, p = 0.22). Prefectures with a pediatric cancer hub hospital had significantly higher utilization than those without (80.9 vs. 50.2 per 100,000; p = 0.046), with Cohen's d = 0.66. In a multi-year view, several prefectures (e.g., Mie, Miyagi, Tokyo) repeatedly maintained higher utilization.

conclusionsThis study examined prefecture-level disparities in pediatric radiotherapy across Japan. The number of board-certified pediatricians was associated with crude treatment counts but not with population-normalized rates, whereas prefectures with a designated pediatric cancer hub hospital showed significantly higher rates. These findings can inform policy making and healthcare resource allocation, particularly efforts to strengthen hub hospitals and cross-prefectural referral networks.

Indexed as

Healthcare DisparitiesNeoplasmsRadiotherapyAdolescentChildChild, PreschoolDatabases, FactualFemaleHumansInfantJapanHealthcare resourcesNational databasePediatric oncologyPediatric radiotherapyRegional disparities

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.