Evidence map›Paper›PMID 42090097›Full record

SynthesisInternational urology and nephrology2026

Laparoendoscopic single-site versus conventional laparoscopic living donor nephrectomy: a systematic review and meta-analysis of randomized controlled trials.

Hanlin Liu, Li Wang, Jianwei Yang, Siyu Chen, Wei Shi, Xiaoran Li

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanlin LiuDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China.
Li WangDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China.
Jianwei YangDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China.
Siyu ChenDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China.
Wei ShiDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China. shiweijust@126.com.
Xiaoran LiDepartment of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, China. lixiaoran05@163.com.

Funding

Health Commission of Gansu Province GSWSQNPY2025-15Natural Science Foundation of Gansu Province 22JR11RA069
6 · The paper itself

Abstract

backgroundLaparoendoscopic single-site donor nephrectomy (LESS-DN) has been proposed as a minimally invasive alternative to conventional laparoscopic donor nephrectomy (CLDN), but its perioperative advantages remain controversial. This meta-analysis aimed to compare the outcomes of LESS-DN and CLDN based on randomized controlled trials (RCTs).

methodsPubMed, Embase, and the Cochrane Library were searched up to August 20, 2025, for English-language RCTs comparing LESS-DN and CLDN. The risk of bias was assessed using the original Cochrane Risk of Bias tool (RoB 1.0), and pooled analyses were performed using Review Manager 5.4.1 software.

resultsFour randomized controlled trials involving 274 donors (LESS-DN, n = 136; CLDN, n = 138) were included. There were no significant differences between groups in operative time, warm ischemia time, estimated blood loss, length of hospital stay, time to extraction, or overall complication rates.

conclusionsBased on the currently available randomized evidence, no statistically significant differences were detected between LESS-DN and CLDN in the perioperative outcomes analyzed in living kidney donors. Further adequately powered, multicenter randomized trials-particularly evaluating postoperative pain, patient-reported recovery, and cosmetic satisfaction-are warranted.

Indexed as

Kidney TransplantationLaparoscopyLiving DonorsNephrectomyTissue and Organ HarvestingHumansRandomized Controlled Trials as TopicDonor nephrectomyLaparoscopicLaparoscopic donor nephrectomyMeta-analysisRandomized controlled trialSingle-site

Identifiers

PMID42090097

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.