Evidence map›Paper›PMID 42090043›Full record

ArticleJournal of fluorescence2026

Radical Quenching and LOX Inhibiting Properties of Indole Derivatives: A Plausible Mechanism of Action Through HAT, SET-PT and SPLET Pathway.

Km Srishti, Oseen Negi, Anamika Gusain, Naresh Kumar, Rahul Kumar Vishwakarma, Prasanta Kumar Hota

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Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Km Srishti *Department of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India.
Oseen Negi *Department of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India.
Anamika GusainDepartment of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India.
Naresh KumarDepartment of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India.
Rahul Kumar VishwakarmaDepartment of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India.
Prasanta Kumar HotaDepartment of Chemistry, School of Sciences, Hemvati Nandan Bahuguna Garhwal University, Srinagar (Garhwal), Uttarakhand, 246174, India. pkhota@chemistry.du.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2-phenylindoles were synthesized and studied the radical quenching properties towards compounds with nitrogen radical. The present indoles exhibit radical quenching properties in a substituent dependent manner through proton and electron transfer mechanisms. ortho-Hydroxy-2-phenylindole and para-hydroxy-2-phenylindole show strong radical quenching properties towards DPPH radical as comparable to vitamin C, whereas meta-hydroxy-2-phenylindole and 2-phenylindole exhibit radical quenching properties with lower efficacy. All these indoles, however, exhibit efficient radical quenching properties towards ABTS radical as comparable to DPPH radical (IC

Indexed as

AntioxidantDensity functional theoryFluorescenceLipoxygenase

Identifiers

PMID42090043

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.