ArticleAesthetic plastic surgery2026
Is Local Tranexamic Acid Worth Using in Hair Transplantation? An Intrapatient Comparison.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
backgroundExcessive bleeding during donor area harvesting may impair surgical control and graft quality in hair transplantation. While adrenaline-based tumescent solutions are routinely used, the additional value of local tranexamic acid (TXA) in this setting remains unclear.
objectiveTo evaluate whether local TXA provides additional benefit compared with standard adrenaline-based tumescence during donor area follicular unit excision (FUE).
methodsThis intrapatient-controlled, single-blinded study included 57 male patients undergoing FUE. In each patient, two adjacent 4 cm
resultsBleeding scores were significantly lower in the adrenaline-only control areas compared with TXA-treated areas (median [IQR] 2 [2-3] vs. 3 [2-4]; p < 0.001), with a large effect size (r = 0.56).
conclusionWithin the specific protocol applied in this study, adrenaline-based tumescence demonstrated more effective immediate intraoperative hemostasis. However, given the difference in total adrenaline exposure between groups, the independent contribution of tranexamic acid cannot be conclusively determined. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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