Evidence map›Paper›PMID 42089676›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

AK8 deficiency causes primary ciliary dyskinesia by disrupting energy homeostasis in the airways.

Dörthe Thüß, Ying Liu, Gerard W Dougherty, Ellie J Maas, Jie He, Xianglin Zhou, André Schultz, Kim G Nielsen, Heymut Omran, Hong Luo and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dörthe ThüßDepartment of General Pediatrics, University Hospital Muenster, Muenster, Germany.
Ying LiuDepartment of Pulmonary and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Gerard W DoughertyDepartment of General Pediatrics, University Hospital Muenster, Muenster, Germany.
Ellie J MaasDermatology Research Centre, Frazer Institute, University of Queensland, Brisbane, Queensland, Australia.
Jie HeDepartment of Pulmonary and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xianglin ZhouDepartment of Pulmonary and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
André SchultzWal-yan Respiratory Research Centre, Kids Research Institute Australia, University of Western Australia, Perth, Western Australia, Australia.
Kim G NielsenDepartment of Pediatrics and Adolescent Medicine, Danish PCD Centre, Danish Pediatric Pulmonary Service, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Heymut OmranDepartment of General Pediatrics, University Hospital Muenster, Muenster, Germany.ORCID 0000-0003-0282-6765
Hong LuoDepartment of Pulmonary and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0002-9501-651X
AK8 Study Group

Funding

AusBREATHE (NHMRC Centre for Research Excellence in Bronchiectasis for Children 1170958Australian Government Department of EducationChildrens Lung Foundation to K.G.N., the Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0529602Deutsche Forschungsgemeinschaft 549467913Deutsche Forschungsgemeinschaft OM6/10Deutsche Forschungsgemeinschaft OM6/7Deutsche Forschungsgemeinschaft OM6/8Federal Ministry of Research, Technology and Space 03LW0648-cuRNAInterdisziplinäres Zentrum für klinische Forschung Münster IZKF Om2/010/20MRFF MRFF1169868National Natural Science Foundation of China 82270048National Natural Science Foundation of China 82400055Natural Science Foundation of Hunan Province 2024JJ3040Natural Science Foundation of Hunan Province 2024JJ6577NHMRC L3 Investigator 2025379Research Training StipendUniversity of Queensland Faculty of Medicine fellowship
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42089676
PMCPMC13519318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.