Evidence map›Paper›PMID 42089426›Full record

ArticleHIV medicine2026

Preference for different PrEP formulations: A cross-sectional study in a PrEP cohort in Spain.

Alfredo Soler-Carracedo, Allison R Webel, Luis Ramos-Ruperto, Rafael Mican-Rivera, Rocio Montejano-Sanchez, Ana Milinkovic, Stephanie A Ruderman, Joseph P De Santis, Jose I Bernardino

Abstract read
In one paragraph

Article in HIV medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alfredo Soler-CarracedoChelsea and Westminster Hospital, London, UK.ORCID https://orcid.org/0000-0002-4561-9435
Allison R WebelUniversity of Washington, Seattle, Washington, USA.
Luis Ramos-RupertoHospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0000-0001-5251-2161
Rafael Mican-RiveraHospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0000-0002-6626-4266
Rocio Montejano-SanchezHospital Universitario La Paz, Madrid, Spain.
Ana MilinkovicChelsea and Westminster Hospital, London, UK.
Stephanie A RudermanUniversity of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-0058-5729
Joseph P De SantisThe University of Miami, Coral Gables, Florida, USA.ORCID https://orcid.org/0000-0001-9144-7876
Jose I BernardinoHospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0000-0003-3501-8529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo gain a better understanding of PrEP-users' preference for long-acting vs. oral PrEP formulation.

methodsFrom April 2023 to January 2024, participants who were prescribed PrEP completed an anonymous, structured, self-administered, cross-sectional survey as part of their routine PrEP care in a hospital setting in Madrid, Spain. Inclusion criteria were attendance at the clinic for PrEP care and the ability to understand the Spanish language. Eligibility was not restricted by age. A convenience sample of 200 participants was used. The ethics committee approved a waiver of written consent. Descriptive statistics and chi-square tests were used to analyse the data.

resultsA sample of 201 participants completed the survey, of which 193 (96.5%) were male and most were 30-39 years old (48.8%). The response rate was estimated to be more than 90%. Among participants, 74.9% preferred LA-PrEP (53.9% preferred a subcutaneous (SC) injection every 6 months and 21.0% preferred an intramuscular (IM) injection every 2 months). Participants reported that LA-PrEP is more practical, indicating fewer visits to the clinic as a primary reason (67.4%). 29.4% of participants were aware of IM LA-PrEP, 10.0% of SC LA-PrEP and 10.4% were familiar with both. Respondents who selected LA-PrEP were more often under 40 years of age (p = 0.016) compared to those who preferred oral PrEP (73.7% vs. 61.2%, respectively). Limitations included the use of a cross-sectional design, a homogeneous sample and the use of one study location, among others.

conclusionLA-PrEP is the preferred form of PrEP for the majority of respondents.

Indexed as

Anti-HIV AgentsHIV InfectionsPatient PreferencePre-Exposure ProphylaxisAdministration, OralAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSpainSurveys and QuestionnairesYoung AdultAnti-HIV Agentsadherencecabotegravirlenacapavirlong‐actingPrEP

Identifiers

PMID42089426
PMCPMC13547426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.