Evidence map›Paper›PMID 42089329›Full record

ReviewBiological reviews of the Cambridge Philosophical Society2026

Humans are not unique: difficult birth is common in placental mammals.

Nicole D S Grunstra

Abstract readReview
In one paragraph

Review in Biological reviews of the Cambridge Philosophical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nicole D S GrunstraDepartment of Evolutionary Biology, University of Vienna, Djerassiplatz 1, Vienna, 1030, Austria.

Funding

Austrian Science Fund ESP 485 (doi: 10.55776/ESP485)
6 · The paper itself

Abstract

Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the 'obstetrical dilemma' have contributed to this assumption by explaining difficult childbirth as the outcome of a unique evolutionary history of bipedalism and encephalisation. However, a comprehensive review of the literature and an analysis of collated data demonstrate that human birth is not truly exceptional in its risk. Dystocia (birth difficulties) occurs across a phylogenetically wide range of placental mammals, including wild populations where natural selection would be expected to minimise its occurrence. Various species show similar or higher dystocia prevalence compared to humans, and fetopelvic disproportion is particularly common in species with precocial, large-bodied offspring. The underlying causes and risk factors are also highly comparable. Contrary to long-standing assumptions, natural selection has not eliminated dystocia in natural mammal populations, suggesting that parturition in placentals may be characterised by a persistent baseline risk of complications. This persistent risk likely reflects a life history trade-off between the improved survival of large offspring and the occasional costs of birth complications. A cliff-edge model of selection can explain the evolutionary dynamics underlying this trade-off and the persistent fraction of fetopelvic disproportion and related forms of obstructive dystocia. An additional trade-off involving litter size is evident in litter-bearing, often altricial species, where both small and large litters increase the risk of dystocia. Phenotypic plasticity further maintains dystocia in populations despite selection, while also contributing to variation in birth difficulty within and among species. These findings reposition human birth difficulties within a broader mammalian pattern rather than as a uniquely human phenomenon requiring exceptional explanations. Reframing human childbirth in this broader context challenges entrenched assumptions and highlights the value of a comparative evolutionary perspective.

Indexed as

DystociaMammalsParturitionAnimalsBiological EvolutionFemaleHumansPregnancychildbirthcliff‐edge selectiondystociafetopelvic disproportionlife‐history trade‐offsmammalsneonatal sizeobstetrical dilemmaobstructed labourpelvis

Identifiers

PMID42089329
PMCPMC13542365

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.