Evidence map›Paper›PMID 42089314›Full record

ArticleAmerican journal of respiratory cell and molecular biology2026

Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cells.

Weston T Powell, Tomasz J Janczyk, Patricia C Dela Cruz, Basilin Benson, Nyssa B Samanas, Elizabeth R Vanderwall, Camille R Gates, Lucille M Rich, Teal S Hallstrand, Matthew C Altman and 1 more

Abstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Weston T PowellCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.ORCID 0000-0002-1555-1425
Tomasz J JanczykSystems Immunology Division, Benaroya Research Institute at Virginia Mason, Seattle, WA, United States.
Patricia C Dela CruzCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.
Basilin BensonSystems Immunology Division, Benaroya Research Institute at Virginia Mason, Seattle, WA, United States.
Nyssa B SamanasCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.
Elizabeth R VanderwallCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.
Camille R GatesCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.
Lucille M RichCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.
Teal S HallstrandCenter for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, United States.
Matthew C AltmanSystems Immunology Division, Benaroya Research Institute at Virginia Mason, Seattle, WA, United States.ORCID 0000-0002-1784-8505
Jason S DebleyCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, WA, United States.ORCID 0000-0001-6438-9535

Funding

The Bioinformatics and Data Management Core (BDMC)U19AI175089 · NIAID · UNIVERSITY OF WASHINGTON · PI JASON S DEBLEY, Teal S Hallstrand · 2023 to 2026
$7.8M
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodelingR01AI163160 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI JASON S DEBLEY · 2022 to 2026
$4.3M
Impact of Heterogeneous Airway Epithelial ACE2 Expression and Interferon Responses on SARS-CoV2 Infectivity and ReplicationK24AI150991 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI DEBLEY, JASON S · 2020 to 2024
$1.2M
Circadian Regulation of Epithelial Immune Reponses in AsthmaK08HL179396 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI Weston Thomas Powell · 2025 to 2026
$310k
NIAID NIH HHS R01 AI163160NIAID NIH HHS U19 AI175089NIH HHS K08HL179396NIH HHS K24AI150991NIH HHS R01AI163160NIH HHS U19AI175089Parker B. Francis FellowshipSleep Research Society
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42089314
PMCPMC13624505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.