Observational studyJournal of the American Heart Association2026
Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re-Myo Study).
Chiara Baggio, Antonio Cannata, Alessio Gasperetti, Enrico Ammirati, Piero Gentile, Giovanni Peretto, Giulio Savonitto, Annagrazia Cecere, Valentino Collini, Maurits Sikking and 22 more
Abstract readMulticenter StudyObservational Study
In one paragraphObservational study in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
32 authors.
Chiara BaggioCentre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste Trieste Italy.ORCID 0000-0002-3075-5813 Antonio CannataKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences London United Kingdom.ORCID 0000-0001-7609-6297 Alessio GasperettiDepartment of Medicine, Division of Cardiology Johns Hopkins School of Medicine Baltimore Maryland USA.ORCID 0000-0003-3432-070X Giulio SavonittoCentre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste Trieste Italy.ORCID 0000-0001-6324-9821 Annagrazia CecereDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua Padua Italy.ORCID 0000-0001-5587-1215 Valentino ColliniDepartment of Medicine, University of Udine and Cardiothoracic Department University Hospital Santa Maria della Misericordia, ASUFC Udine Italy.ORCID 0000-0003-0008-4630 Maurits SikkingDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM) Maastricht University Medical Centre Maastricht The Netherlands.ORCID 0000-0001-8165-6631 Raffaella MistrulliCardiology Unit, Department of Clinical and Molecular Medicine Sapienza University of Rome, Sant'Andrea University Hospital Rome Italy.ORCID 0000-0001-7218-9891 Erika PagannoneCardiology Unit, Department of Clinical and Molecular Medicine Sapienza University of Rome, Sant'Andrea University Hospital Rome Italy.ORCID 0009-0008-4695-9440 Dörthe SchmidtUniversity Heart Centre Zurich Department of Cardiology Zurich Switzerland.
Jessica ArticoBarts Heart Centre, Barts Health NHS Trust, West Smithfield London, United Kingdom; Institute of Cardiovascular Science, University College London London United Kingdom.
Enrico FabrisCentre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste Trieste Italy.ORCID 0000-0001-9458-0736 Martina Perazzolo MarraDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua Padua Italy.ORCID 0000-0001-7645-6993 Daniel I BromageKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences London United Kingdom.ORCID 0000-0002-4243-5964 Paul A ScottKing's College London British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine & Sciences London United Kingdom.ORCID 0009-0002-3044-5986 Job A J VerdonschotDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM) Maastricht University Medical Centre Maastricht The Netherlands.ORCID 0000-0001-5549-1298 Saidi MohiddinBarts Heart Centre, Barts Health NHS Trust, West Smithfield London, United Kingdom; Institute of Cardiovascular Science, University College London London United Kingdom.ORCID 0000-0002-1031-4084 Massimo ImazioDepartment of Medicine, University of Udine and Cardiothoracic Department University Hospital Santa Maria della Misericordia, ASUFC Udine Italy.ORCID 0000-0002-5722-0245 Stephane HeymansDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM) Maastricht University Medical Centre Maastricht The Netherlands.ORCID 0000-0001-9477-7803 Gianfranco SinagraCentre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste Trieste Italy.ORCID 0000-0003-2700-8478 Merlo MarcoCentre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste Trieste Italy.ORCID 0000-0002-1022-3131 Member of ERN Guard Heart Network
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundRecurrence of acute myocarditis (AM) is challenging. The management and natural history of patients who experience a recurrence of AM (Re-AM) remain poorly characterized. The aim of this study is to investigate clinical characteristics and outcomes of patients with Re-AM.
methodsIn this international multicenter study, 141 consecutive patients with biopsy-proven or cardiac magnetic resonance-proven Re-AM (35 [26-45] years, 77% male, median left ventricular ejection fraction 55%) were investigated and compared with 372 consecutive patients with single acute myocarditis (S-AM). The primary outcome was a composite of all-cause mortality, heart transplant and major ventricular arrhythmias.
resultsPatients with Re-AM had more frequently a family history of cardiomyopathy (19% in Re-AM versus 2.8% in S-AM,
conclusionsRe-AM is a distinct clinical subgroup of AM associated with generally worse prognosis and a specific increased arrhythmic risk compared with S-AM.
Indexed as
MyocarditisAcute DiseaseAdultArrhythmias, CardiacBiopsyFemaleHeart TransplantationHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedPrognosisRecurrenceRisk FactorsStroke Volumecardiac magnetic resonancecardiomyopathymyocarditisprognosisrecurrent
Identifiers
PMID42089151
PMCPMC13279631
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