Evidence map›Paper›PMID 42089083›Full record

ArticleCurrent addiction reports2025

Context-dependent Impulsivity in Substance Use Disorder: A Neuroscience-informed Framework.

Tara Rezapour, Nastaran Nafissi, Parnian Rafei, Jasmin Vassileva, Hamed Ekhtiari

Abstract read
In one paragraph

Article in Current addiction reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tara RezapourInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, USA.
Nastaran NafissiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Parnian RafeiTrinity College Institute of Neuroscience (TCIN), Trinity College Dublin, Dublin, Ireland.
Jasmin VassilevaInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, USA.
Hamed EkhtiariDepartment of Psychiatry, University of Minnesota, MN, USA.

Funding

Varieties of Impulsivity in Opiate and Stimulant UsersR01DA021421 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI VASSILEVA, JASMIN L · 2008 to 2025
$6.5M
Utility of adaptive design optimization for developing rapid and reliable behavioral paradigms for substance use disordersR01DA058038 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Woo-Young Ahn, JASMIN L VASSILEVA · 2023 to 2026
$2.1M
NIDA NIH HHS R01 DA021421NIDA NIH HHS R01 DA058038
6 · The paper itself

Abstract

Purpose of review: Due to various reasons including psychobiological states and psychopathological conditions, individuals may be more inclined toward choices or actions that are known as impulsive. This preference arises from either or both personality characteristics ( Recent findings: By integrating evidence from classic neuropsychological measures and the drug-cue reactivity paradigm in the field of addiction, we propose a neuroscience-informed conceptual framework explaining how relapse may occur due to the disruption of neurocognitive mechanisms in response to contextual cues. We introduce the term 'context-dependent impulsivity' in accordance with the cue-reactivity paradigm as a marker of addiction recovery and as a mechanistic target for cue-based interventions such as cognitive bias modification and mindfulness-based relapse prevention. Summary: Context-dependent impulsivity is a multi-faceted construct, which could be characterized by specific cognitive phenotypes. Parsing these different phenotypes into their constituent neurocognitive mechanisms and examining their interactions with relapse vulnerability could inform clinicians about optimized cognitive interventions and neuropsychological assessments tailored to individuals with specific impulsivity phenotypes within the trait or state levels.

Indexed as

Addiction treatmentContext-dependent impulsivityNeurocognitive processesSubstance use disorders

Identifiers

PMID42089083
PMCPMC13138723

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.