Evidence map›Paper›PMID 42089006›Full record

ArticleTrauma case reports2026

Ovine forestomach matrix as a novel adjunct to promote healing of low output enterocutaneous fistulae in high-risk surgical patients.

Sophia Trinh, Joseph Mason, Paige Deville, Dhanushka Vitharana, John Hunt, Alan Marr, Lance Stuke, Patrick Greiffenstein, Alison Smith

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PubMed Full text at PMC Publisher
In one paragraph

Article in Trauma case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sophia TrinhDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Joseph MasonDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Paige DevilleDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Dhanushka VitharanaDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
John HuntDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Alan MarrDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Lance StukeDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Patrick GreiffensteinDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Alison SmithDepartment of Surgery, 8th Floor, 2021 Perdido Street, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The development of enterocutaneous fistulas (ECF) after emergency laparotomies is not uncommon. Management is difficult and options limited. Studies suggest ovine forestomach matrix (OFM) grafts may be viable treatment options for complex wounds. The goal of this study was to investigate the use of OFM in the treatment of ECFs. Methods: Patients with ECFs as a result of emergency laparotomy were treated with OFM. Wounds were appropriately debrided and OFM was applied. A secondary dressing was applied and left on for a minimum of 7 days. Patients were followed at regular intervals to monitor progression of wound healing. Results: Three patients were included in the case series. One patient developed ECF after bowel resection secondary to gunshot wounds. OFM was applied and upon follow up, the wound was significantly healed. The second patient developed ECF after bowel resection secondary to being struck by a vehicle. OFM was applied and at two week follow up the fistula was closed. The third patient developed ECF after major small bowel resection secondary to acute mesenteric ischemia. OFM was applied and the ECF was fully closed at one month. Conclusion: This case series highlights the utilization of OFM to augment wound healing in patients with ECFs. This pilot study demonstrates the excellent results achieved with OFM as an adjunct for difficult wounds such as ECFs with the ability to accelerate healing.

Indexed as

EnterocutaneousFistulaLaparotomyOvine forestomach matrix

Identifiers

PMID42089006
PMCPMC13136757

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.