ReviewPatient preference and adherence2026
Person-Centered Approaches for Identifying Subgroups of Post-Stroke Depression: A Systematic Review of Observational Studies.
Review in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Current management for post-stroke depression (PSD) mainly relies on the severity of depression, insufficiently capturing PSD's clinical heterogeneity. No previous systematic review has jointly synthesized cross-sectional and longitudinal observational studies using person-centered approaches to identify PSD subgroups. This systematic review synthesizes evidence from these studies employing person-centered approaches to characterize PSD subgroups. Methods: Comprehensive searches were conducted in nine databases from the inception to September 2025. Observational studies using person-centered approaches to subgroup PSD were included. Two reviewers independently performed data extraction and study quality assessment using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Results: Eleven articles (9 unique cohorts; N = 6729) were included. Cross-sectional studies (4 studies; N = 1400) identified four symptom-based subgroups: low depressive symptoms (46.6%), emotional depressive symptoms (9.4%), atypical depressive symptoms (23.2%), and widespread depressive symptoms (20.8%). Longitudinal studies (5 studies; N = 5329) revealed four trajectory-based subgroups: low and stable/decreasing (59.7%), low but increasing (17.8%), high and stable/increasing (13.6%), and initially high/moderate but declining (8.9%). Latent transition analysis (2 studies; N = 886) showed greater subgroup fluidity within 6-month post-stroke, followed by increasing stability. Predictors of more severe/persistent subgroups included social-demographic, clinical and physiological factors. One study found that all non-low-stable trajectories were associated with significantly increased 10-year mortality (hazard ratios: 1.38-2.62). Conclusion: Person-centered approaches can effectively delineate latent subgroups of PSD characterized by distinct symptom manifestations and trajectories. Findings of this review support a shift away from one-size-fits-all, total-score-based management toward a more nuanced, symptom- and trajectory-informed framework for PSD. Systematic Review Registration: CRD420251273568.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.