Evidence map›Paper›PMID 42088844›Full record

ArticleCase reports in cardiology2026

Cardiac Tamponade-A Rare Manifestation of Ruxolitinib Discontinuation Syndrome: A Case Report.

Shariq Hamid, Rory Bennet, Jessica Yao, Joshua Wong

Abstract read
In one paragraph

Article in Case reports in cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shariq HamidDepartment of General Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia, mh.org.au.ORCID https://orcid.org/0009-0007-8409-7717
Rory BennetDepartment of Haematology, Royal Melbourne Hospital, Parkville, Victoria, Australia, mh.org.au.ORCID https://orcid.org/0000-0003-4037-4536
Jessica YaoDepartment of Cardiology, Royal Melbourne Hospital, Parkville, Victoria, Australia, mh.org.au.ORCID https://orcid.org/0000-0001-8974-4265
Joshua WongDepartment of Cardiology, Royal Melbourne Hospital, Parkville, Victoria, Australia, mh.org.au.ORCID https://orcid.org/0000-0002-9824-8746

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 52-year-old gentleman presenting with tachycardia was found to have a large pericardial effusion and cardiac tamponade. This case was on a background of long-standing myelofibrosis managed with ruxolitinib, which was recently withheld for an orthopaedic procedure. He was diagnosed with presumed ruxolitinib discontinuation syndrome (RDS), resulting in a large pericardial effusion due to an increased inflammatory response. He was managed with a pericardial window and prompt recommencement of ruxolitinib and steroids. This case highlights the importance and increasing prevalence of RDS with the serious consequence of cardiac tamponade. Symptoms of RDS should be recognised and managed with recommencement of a JAK inhibitor and steroids.

Identifiers

PMID42088844
PMCPMC13137292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.