Evidence map›Paper›PMID 42088729›Full record

ReviewIranian endodontic journal2026

Cytocompatibility of Three Calcium Silicate-Based Biomaterials: A Systematic Review and Meta-Analysis.

Sahar Shabani Panbeh Choleh, Mahmoud Heidari, Ezatolah Kazeminejad, Masoud Mohammadi, Abdolhalim Rajabi

Abstract readReview
In one paragraph

Review in Iranian endodontic journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sahar Shabani Panbeh CholehCellular and Molecular Biology, Department of Biology, Go.C., Islamic Azad University, Gorgan, Iran.
Mahmoud HeidariDepartment of Biology, Go.C., Islamic Azad University, Gorgan, Iran.
Ezatolah KazeminejadDental Research Center, Jorjani Clinical Sciences Research Institute, Golestan University of Medical Sciences, Gorgan, Iran.
Masoud MohammadiGolestan Research Center of Gastroenterology and Hepatology, Jorjani Clinical Sciences Research Institute, Golestan University of Medical Sciences, Gorgan, Iran.
Abdolhalim RajabiHealth Management and Social Development Research Center, Golestan university of medical sciences, Gorgan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To systematically evaluate and compare the Materials and Methods: A comprehensive search was conducted in PubMed, Scopus, Web of Science, Cochrane, ProQuest, Wiley, and Ovid (including Embase) for Results: Among 8,004 screened records, 32 studies met the inclusion criteria, with 11 included in the meta-analysis. Overall, no significant differences in cytotoxicity were identified among Mineral Trioxide Aggregate (MTA), Biodentine, and Calcium-Enriched Mixture (CEM) cement. Nevertheless, undiluted MTA and Biodentine at a 1:4 dilution were associated with a statistically significant reduction in cell viability at 48 hours ( Conclusion: These findings indicate that MTA, Biodentine, and CEM cement generally exhibit acceptable

Indexed as

BiocompatibilityBiodentineCEM CementCytotoxicityMTAVital Pulp Therapy

Identifiers

PMID42088729
PMCPMC13136708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.