ArticleOrthopedic research and reviews2026
Efficacy of Modified Transforaminal Lumbar Interbody Fusion in Three-Planar Correction for Severe Adult Spinal Deformity: Radiographic and Clinical Outcomes.
Article in Orthopedic research and reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adult spinal deformity (ASD) significantly impacts quality of life in geriatric populations due to severe sagittal imbalance, degenerative scoliosis, and associated neurological compression that usually requires surgery when conservative treatment fails. Objective: To evaluate the clinical and radiological outcome of a modified transforaminal lumbar interbody fusion (TLIF) technique in the three-planar correction of severe adult spinal deformity (ASD). Methods: This was a single-center case series study. We recruited 72 ASD patients (mean age 64.5 years) with at least one of the following criteria met (SRS-Schwab sagittal modifier ++; Cobb angle >30°; Coronal vertical axis >3cm) operated between January 2020 and May 2025. The surgical protocol involved four modifications: (1) bilateral facetectomy and posterior column resection; (2) a concave-side approach to the disc space; (3) anterior positioning of the PEEK cage; and (4) supplemental bone grafting posterior to the cage. Clinical and radiological outcomes were evaluated at a mean follow-up of 2.3 years. Results: Significant improvements were observed in SRS-22 (2.6 to 3.7) and NCOS (43 to 74.5) scores (p < 0.05). After surgery, both PI-LL mismatch and the Cobb angle have been markedly improved (35° down to 17° and 21.5° down to 5°, respectively). The fusion rate was 90% at 1 year. Univariate analysis identified osteoporosis (OR = 13.4, p<0.05), "pear-shaped" disc morphology (OR = 14, p<0.05), and PI > 65° (OR = 13.7, p<0.05) as significant risk factors for unchanged sagittal modifier after surgery. Early complications included infection (2.7%) and pneumonia (2.7%) whereas the main mid-term adverse event was PJK (15%). Conclusion: Modified TLIF is associated with improvement of mid-term radiographic and clinical outcomes and an acceptable complication rate. Additional research involving larger cohorts and extended follow-up, preferably with a control group, is required to reach more definitive conclusions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.