Evidence map›Paper›PMID 42088716›Full record

ReviewFrontiers in human neuroscience2026

In-ear EEG wearables for brain activity assessment and cognitive rehabilitation: the emerging role of multimodal embedded intelligence.

Asma Channa, Herbert F Jelinek, Abdelkader Nasreddine Belkacem, Mohamed Atef, Ibrahim Abe M Elfadel

Abstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asma ChannaCenter for Cyber Physical Systems and Department of Computer and Information Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Herbert F JelinekDepartment of Clinical Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
Abdelkader Nasreddine BelkacemDepartment of Computer and Network Engineering, United Arab Emirates University, Abu Dhabi, United Arab Emirates.
Mohamed AtefDepartment of Electrical and Communication Engineering, United Arab Emirates University, Abu Dhabi, United Arab Emirates.
Ibrahim Abe M ElfadelCenter for Cyber Physical Systems and Department of Computer and Information Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This literature review critically examines the design, validation, and application of non-invasive in-ear electroencephalography (ear-EEG) systems as emerging wearable platforms for long-term neurophysiological monitoring and intervention. Following PRISMA guidelines, studies published between 2010 and 2025 were systematically selected from four major databases and organized into four thematic domains: in-ear wearable system design and validation, multimodal sensing and stimulation, embedded intelligence, and brain-state monitoring and rehabilitation. The review focuses exclusively on wearable, ear-centered EEG technologies, explicitly excluding cochlear implants and other invasive or behind-the-ear systems. We analyze key engineering challenges unique to ear-EEG, including electrode placement constraints, mechanical-electrical coupling, motion robustness, power efficiency, and long-term wearability. The review highlights a growing transition toward compact, wireless ear-EEG systems with on-device signal processing and embedded machine learning, enabling real-time brain-state estimation under ambulatory conditions. Multimodal integration, combining ear-EEG with complementary sensors such as EOG, inertial units, and cardiovascular signals is shown to improve artifact awareness, contextual interpretation, and closed-loop capability. Beyond summarizing existing technologies, this review identifies critical gaps limiting clinical translation, including the lack of standardized validation protocols, limited embedded autonomy, and underexplored closed-loop neurofeedback and neuromodulation architectures. By synthesizing advances across hardware design, signal processing, and intelligent system integration, this work provides a systems-level roadmap for the future development of wearable, intelligent, and clinically robust ear-EEG platforms for mental health, neurorehabilitation, and continuous brain monitoring.

Indexed as

brain activitycognitive monitoringcognitive rehabilitationEEGembedded intelligencein-ear wearable devicestimulationsystem design

Identifiers

PMID42088716
PMCPMC13137128

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.