Evidence map›Paper›PMID 42088559›Full record

ArticleBioactive materials2026

Sonogenetic flexible nanogels enabling enhanced calcium overload-induced immunogenic cell death for tumor immunotherapy.

Bicheng Han, Zideng Dai, Qing Liu, Xue Li, Fuhao Jia, Xi Deng, Ruizhi Tian, Mingliang Ning, Hangrong Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bicheng HanState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Zideng DaiDepartment of Electrical and Computer Engineering, The University of Hong Kong, Hong Kong SAR, China.
Qing LiuState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Xue LiState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Fuhao JiaState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Xi DengState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Ruizhi TianState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Mingliang NingState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.
Hangrong ChenState Key Laboratory of High Performance Ceramics, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonogenetics represents a non-invasive and precise strategy for cancer therapy by coupling ultrasound (US) with genetic engineering. However, achieving efficient deep-tumor delivery and profound immune activation remains challenging. Herein, we developed a novel sonogenetic nanogel system (NGs@pDNA) designed to trigger a potent systemic antitumor immune response via US-induced calcium (Ca

Indexed as

Calcium overloadFlexible nanogelImmunotherapyMechanosensitive channelsSonogenetic

Identifiers

PMID42088559
PMCPMC13138074

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.