Effects of Batri-7 on fallopian tube tissues in a rat model of salpingitis based on the toll-like receptor 4/myeloid differentiation factor 88/nuclear factor kappa B signalling pathway.

Rong Yu, Qiutong Wu, Yanhua Xu, Tianling Xiao, Sachurila, Hui Li, Genyu Li

Abstract read

In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rong Yu *Integrated Traditional Chinese and Western Medicine Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Integrated Traditional Chinese and Western Medicine Gynecology, Tongliao, Inner Mongolia, China.

Qiutong Wu *Integrated Traditional Chinese and Western Medicine Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Integrated Traditional Chinese and Western Medicine Gynecology, Tongliao, Inner Mongolia, China.

Yanhua XuPharmaceutical Clinical Trial Institution, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.

Tianling XiaoDepartment of Gynecology, Baotou Central Hospital, Baotou, Inner Mongolia, China.

SachurilaIntegrated Traditional Chinese and Western Medicine Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Integrated Traditional Chinese and Western Medicine Gynecology, Tongliao, Inner Mongolia, China.

Hui LiSchool of Clinical Medicine, Inner Mongolia Minzu University, Tongliao, China.

Genyu LiIntegrated Traditional Chinese and Western Medicine Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Integrated Traditional Chinese and Western Medicine Gynecology, Tongliao, Inner Mongolia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore the underlying mechanism of Batri-7 in tubal inflammatory infertility model rats treatment in the toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear factor kappa B (NF-κB) pathway. Methods: Fifty-three specific-pathogen-free-grade female Sprague-Dawley rats were selected, of which 10 were randomly assigned to the blank control group (normal rats). The remaining 43 rats were used to establish a salpingitis model, induced by mixed bacteria, and were randomly divided into a model group, a positive control group, a low-dose experimental group and a high-dose experimental group. The rats in the blank and model groups were gavaged with 10 mL·kg Results: Compared with the model group, the high-dose experimental group, the low-dose experimental group and the positive control group could significantly reduce the expression levels of IL-1β, ICAM-1 and TNF-α in plasma, increase the expression level of IL-10 ( Conclusion: Batri-7 can exert anti-inflammatory effects and treat salpingitis by regulating the TLR4/MyD8/NF-κB signalling pathway.

Indexed as

Fallopian TubesMyeloid Differentiation Factor 88NF-kappa BSalpingitisSignal TransductionToll-Like Receptor 4AnimalsCytokinesDisease Models, AnimalFemaleIntercellular Adhesion Molecule-1RatsRats, Sprague-DawleyCytokinesIntercellular Adhesion Molecule-1Myd88 protein, ratMyeloid Differentiation Factor 88NF-kappa BTlr4 protein, ratToll-Like Receptor 4Batri-7gavageproinflammatory factortoll-like receptor 4/myeloid differentiation factor 88/nuclear factor kappa B signalling pathwaytubal inflammatory infertility

Identifiers

PMID42088488

DOI10.3389/fimmu.2026.1672173

PMCPMC13135948

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