Evidence map›Paper›PMID 42088487›Full record

ArticleFrontiers in immunology2026

Case Report: Facial-limited eosinophilic annular erythema in a patient with rheumatoid arthritis: successful treatment with tofacitinib.

Man-Ning Wu, Ying Wang, Yan-Ping Bai, Lei Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Man-Ning WuBeijing University of Chinese Medicine, Beijing, China.
Ying WangDepartment of Dermatology, China-Japan Friendship Hospital, National Center for Integrative Medicine, Beijing, China.
Yan-Ping BaiDepartment of Dermatology, China-Japan Friendship Hospital, National Center for Integrative Medicine, Beijing, China.
Lei WangDepartment of Dermatology, China-Japan Friendship Hospital, National Center for Integrative Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 67-year-old man with rheumatoid arthritis (RA) presenting with symmetrical annular plaques confined to the face. Histopathology demonstrated dense dermal eosinophilia without flame figures, consistent with eosinophilic annular erythema (EAE). Unlike the typical truncal distribution, lesions were limited to the face, a presentation reported in approximately 3% of cases. The patient was successfully treated with tofacitinib, a Janus kinase (JAK) inhibitor. This report illustrates a rare facial variant of EAE and supports the efficacy of JAK inhibition in patients with concurrent RA.

Indexed as

Arthritis, RheumatoidEosinophiliaErythemaJanus Kinase InhibitorsPiperidinesPyrimidinesSkin Diseases, GeneticAgedFaceHumansMaleTreatment OutcomeJanus Kinase InhibitorsPiperidinesPyrimidinestofacitinibeosinophilic annular erythemafacial lesionsJAK inhibitorsrheumatoid arthritistofacitinib

Identifiers

PMID42088487
PMCPMC13136255

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.