Evidence map›Paper›PMID 42088402›Full record

ArticleRadiology case reports2026

Presumed fibrocartilaginous embolism causing spinal cord infarct in 8-year-old female: A case report.

Jay Kakadiya, Dhairya A Lakhani, Siddhartha Gaddamanugu, Fabricio G Goncalves, Alexander J Mullen

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Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jay KakadiyaNeuroradiology Section, Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL.
Dhairya A LakhaniDepartment of Neuroradiology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV.
Siddhartha GaddamanuguDepartment of Radiology, Children's Hospital of Alabama, Birmingham, AL.
Fabricio G GoncalvesDepartment of Radiology, Children's Hospital of Alabama, Birmingham, AL.
Alexander J MullenNeuroradiology Section, Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrocartilaginous embolism (FCE) is a rare, underrecognized cause of spinal cord infarction (SCI) resulting from embolic migration of nucleus pulposus material into the spinal vasculature. It is characterized by acute myelopathy, often following minor trauma or exertion, with diagnosis often challenging due to its rarity and nonspecific features. We report the case of an 8-year-old previously healthy girl who presented with spontaneous hyperacute quadriparesis, back pain, and bowel and bladder dysfunction. MRI revealed longitudinally extensive T2-weighted hyperintensity extending from C5-T8, predominantly involving the ventral cord, with corresponding diffusion restriction and a C6-C7 disc protrusion. Following empiric steroids and plasmapheresis, she demonstrated progressive, near-complete neurological recovery. This case highlights a rare pediatric presentation of FCE-associated SCI without an identifiable inciting event. Although prognosis is often poor, early recognition of suggestive clinical and radiologic features (particularly longitudinal ventral cord involvement with the "owl's eye" sign and associated discovertebral pathology) and timely supportive therapy may result in substantial functional recovery.

Indexed as

Case ReportFibrocartilaginous embolismIschemic MyelopathyOwl’s eye signSpinal Cord Infarct

Identifiers

PMID42088402
PMCPMC13137137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.