ArticleStroke (Hoboken, N.J.)2026
Medical Complications After Mechanical Thrombectomy: Analysis of Trends in US Admissions From 2010 to 2022.
Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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15 authors.
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Abstract
backgroundThe prevalence of medical complications in patients with acute ischemic stroke undergoing mechanical thrombectomy (MT) is sparse. This study aims to quantify and evaluate trends in common medical complications in acute ischemic stroke MT hospitalizations in the United States over the past decade.
methodsWe utilized the 2010 to 2022 Nationwide Inpatient Sample (NIS) to conduct a serial cross-sectional study. All adult acute ischemic stroke MT hospitalizations (aged ≥18 years) were identified using
resultsAmong 233 812 weighted MT hospitalizations (50.3% women; mean age 68.9 years), 35.9% had at least 1 complication. The age and sex-standardized prevalence was highest for acute renal failure (15.6%), UTI (11.3%), and pneumonia (6.8%), whereas acute myocardial infarction (4.7%), GIB (2%), deep venous thrombosis (4.3%), and pulmonary embolism (1.9%) were less common. Disparities in complication burden were present by age/sex (GIB: women 18-39 years, 0.9%; men ≥80 years, 2.7%). Age/sex-standardized prevalence of acute renal failure increased ≈2-fold across the study period from 11.0% in 2010 to 18.5% in 2022, whereas prevalence of sepsis, pulmonary embolism, and acute myocardial infarction also increased marginally over time (all
conclusionsThe prevalence of pneumonia and UTI declined, whereas acute renal failure prevalence more than doubled in acute ischemic stroke MT hospitalizations over the last decade. Complications were consistently linked to poorer discharge outcomes and higher in-hospital mortality, underscoring the need for targeted prevention strategies to optimize postthrombectomy care.
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