ArticleStroke (Hoboken, N.J.)2026
Detecting Basilar Artery Wall Pathology in Isolated Pontine Infarction With Short-TE SWI Magnitude Images.
Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIntracranial atherosclerotic ischemic stroke often involves plaques without luminal stenosis. Existing imaging techniques struggle to detect vessel wall pathology effectively. This study evaluates short-echo time susceptibility-weighted imaging magnitude images (STE-MI) for identifying cerebral microbleeds and reducing artifacts around the basilar artery (BA) compared with susceptibility-weighted angiography (SWAN), enabling its application in detecting BA wall pathology in acute isolated pontine infarction, particularly in patients with nonstenotic noncardioembolic disease.
methodsThis study presents a retrospective analysis of an ongoing prospective observational brain vascular imaging study focused on intracranial atherosclerosis in patients with acute ischemic stroke. Conducted from March 2022 to March 2025, imaging was performed using a 3.0 T magnetic resonance imaging scanner with advanced protocols, including SWAN and STE-MI sequences. The study evaluated cerebral microbleed detection, artifact reduction, and vessel wall imaging quality, with interobserver agreement assessed using Cohen
resultsAmong 33 subjects, STE-MI detected 86% of the microbleeds identified by SWAN, with excellent interobserver agreement (Cohen
conclusionsSTE-MI effectively minimizes artifacts and detects BA wall pathology in acute isolated pontine infarction, particularly in nonstenotic noncardioembolic stroke. This approach may enhance the identification of culprit lesions, potentially improving risk stratification and guiding targeted therapeutic strategies.
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