ArticleUrology annals
Use of autologous platelet-rich plasma in short-segment urethral stricture (a comparative study): Experience in a tertiary care hospital.
Article in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Optical internal urethrotomy (OIU) remains a common intervention for short-segment urethral stricture, but recurrence rates remain high. Platelet-rich plasma (PRP), rich in bioactive growth factors, may enhance wound healing and reduce fibrosis. This study evaluates the impact of submucosal autologous PRP injection as an adjunct to OIU. Methodology: In this prospective comparative study, 64 patients with short-segment urethral stricture (<2 cm) were randomized into two equal groups: OIU alone (control) and OIU with submucosal PRP injection (PRP group). Four milliliters of autologous PRP were injected at eight submucosal sites after urethrotomy. Primary outcome was postoperative maximum flow rate (ml/min) (Qmax) at 6 months. Nonparametric statistics (Mann-Whitney U-test) were used. Results: Baseline demographics and preoperative flow parameters were comparable between groups ( Conclusion: Submucosal PRP injection significantly enhances postoperative urinary flow following OIU. Its regenerative and antifibrotic properties suggest a promising role as an adjunct therapy. Larger trials with long-term follow-up are needed to determine durability of benefit and recurrence outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.