Evidence map›Paper›PMID 42088080›Full record

ArticleEuropean urology open science2026

EAU-ESPU-ERN eUROGEN-ERN ITHACA-ERN ERKNet-IFSBH Guidelines on Spinal Dysraphism in Children and Adolescents: Summary of the Guideline.

Christian Radmayr, Kate Abrahamsson, Guy Bogaert, Michaela Dellenmark-Blom, Wout Feitz, Anju Goyal, Jean-Marie Jouannic, Rianne Lammers, Michal Maternik, Giovanni Mosiello and 9 more

Abstract read
In one paragraph

Article in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Christian RadmayrPaediatric Urology, Medical University, Innsbruck, Austria.
Kate AbrahamssonChildren's and Women's Health, Sahlgrenska University Hospital, Gothenburg, Sweden.
Guy BogaertDepartment of Urology, University of Leuven, Leuven, Belgium.
Michaela Dellenmark-BlomDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, Department of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.
Wout FeitzPaediatric Urology, Radboudumc Amalia Children's Hospital, Nijmegen, The Netherlands.
Anju GoyalRoyal Manchester Children's Hospital, Paediatric Urology, Manchester, United Kingdom.
Jean-Marie JouannicAPHP Sorbonne University, Fetal Medicine Department, Paris, France.
Rianne LammersDepartment of Urology, University Medical Center Groningen, Groningen, The Netherlands.
Michal MaternikPediatrics, Nephrology and Hypertension, Medical University of Gdansk, ERKNet Centre University Clinical Centre (UCK) Gdansk, Poland.
Giovanni MosielloDivision of Neuro-Urology, Bambino Gesù Children's Hospital and Research Institute, Rome, Italy.
Sylvia RoozenInternational Federation for Spina Bifida and Hydrocephalus, Brussels, Belgium.
Ulla SillenQueen Silvia Children's Hospital, Institute of Clinical Sciences, Department of Pediatric Surgery, Pediatric Uronephrology Center, Gothenburg, Sweden.
Raimund SteinUniversity Medical Center, Medical Faculty Mannheim, Heidelberg University, Center for Pediatric Adolescent and Reconstructive Urology, Mannheim, Germany.
Serdar TekgülDepartment of Urology, Division of Pediatric Urology, Hacettepe University, Ankara, Turkey.
Lisette 't HoenDepartment of Pediatric Urology, Erasmus Medical Center, Rotterdam, The Netherlands.
Alexander Von GontardParent-Child and Adolescent Department, Hochgebirgsklinik Davos, Davos, Switzerland.
Johan Vande WalleGhent University, ERKNet Centre - Ghent, Ghent, Belgium.
Yuhong YuanDepartment of Medicine, London Health Science Centre, London, Ontario, Canada.
Rien J M NijmanChildren's and Women's Health, Sahlgrenska University Hospital, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Neurogenic bladder in children and adolescents presents complex challenges requiring comprehensive management strategies. Traditional guideline development often lacks input from diverse stakeholders, potentially overlooking crucial aspects of care. We present a novel approach to guideline development that integrates perspectives from pediatric urologists, nephrologists, psychiatrists, and patient representatives from the very beginning of the guideline development process. For this purpose, the European Association of Urology (EAU) Paediatric Urology Guidelines Panel worked together with European Reference Networks (eUrogen, ITHACA, ERKNet), the ESPU (European Society for Paediatric Urology), as well as the International Federation for Spina Bifida and Hydrocephalus (IFSBH), a professional organization with global coverage for people living with disabilities. Methods: A broad literature search was performed covering the timeframe from 2020 to 2024. Recommendations were developed and rated as strong or weak, based on the quality of the evidence, benefit/ harm ratio, and potential patient preferences. Key findings and limitations: Spinal cord disorders have a profound impact on urinary, renal, and bowel functions, as well as on sexuality and fertility issues, necessitating lifelong management to preserve quality of life and prevent complications, such as urinary tract deterioration in individuals with spinal dysraphism. Timely diagnosis and appropriate multidisciplinary therapeutic management are critical, with comprehensive clinical evaluations-such as urodynamic studies-playing a central role. Treatment strategies should be individualized, incorporating a multidisciplinary approach that addresses not only medical and functional aspects but also considerations related to sexuality and fertility. Continuous monitoring and follow-up care underscore the significance of sustained management for patients with spinal dysraphism. Conclusions and clinical implications: This summary of the 2025 EAU/ESPU/ERN eUrogen/ERN ITHACA/ERN ErkNet/IFSBH guideline provides updated guidance for evidence-based management of children and adolescents with spinal dysraphism.

Indexed as

AnticholinergicsBladder augmentationBladder neck reconstructionConservative treatmentEAU guidelineMitrofanoff stomaNeurogenic bladderSling procedureSpina bifidaSpinal dysraphismUrinary diversion

Identifiers

PMID42088080
PMCPMC13136771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.