Evidence map›Paper›PMID 42088048›Full record

ArticleFrontiers in plant science2026

Ethylene represses jasmonate signaling to attenuate nicotine biosynthesis in

Yongqiang Ding, Yulong Gao, Lu Zhao, Wenjing Wang, Ahui Tong, Bingwu Wang

Abstract read
In one paragraph

Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yongqiang Ding *Tobacco Breeding and Biotechnology Research Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Yulong Gao *Tobacco Breeding and Biotechnology Research Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Lu ZhaoTobacco Breeding and Biotechnology Research Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.
Wenjing WangTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao, China.
Ahui TongKunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Bingwu WangTobacco Breeding and Biotechnology Research Center, Yunnan Academy of Tobacco Agricultural Sciences, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been known for many years that ethylene represses Jasmonic acid (JA)-induced nicotine biosynthesis. However, it is unclear whether ethylene (ET) alone can inhibit nicotine biosynthesis, and if so, how it achieves this. In this study, we found that ethylene alone can suppress nicotine accumulation and the expression of nicotine biosynthesis and transport genes in tobacco. We then performed transcriptome analysis to explore the underlying molecular mechanism. Results showed that over 6000 differentially expressed genes (DEGs) after 2, 4, 8 and 24 h treatment of ethephon, an ethylene-releasing compound, were identified. GO and KEGG enrichment analysis revealed that DEGs were enriched in pathways related to nicotine biosynthesis, including "pyridine nucleotide metabolic process" and "pyridine-containing compound metabolic process" 4 h after ethephon treatment. Further analysis revealed that expression of key regulators of JA-mediated nicotine biosynthesis was significantly altered by ethephon treatment. Specifically, CORONATINE-INSENSITIVE 1 (COI1) genes

Indexed as

ethylenenicotine biosynthesisregulationtobaccotranscriptome analysis

Identifiers

PMID42088048
PMCPMC13136284

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.