Evidence map›Paper›PMID 42087997›Full record

ArticleFrontiers in veterinary science2026

Diagnosis and investigation of infertility causes in two female giant pandas using multimodal techniques: a case report.

Ying Zhou, Honglin Wu, Jin Shu, Yingmin Zhou, Xiangqian Meng, Guiquan Zhang, Xinyu Lv, Guo Li, Ping Lei, Ming He and 6 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Ying Zhou *Sichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Honglin Wu *China Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Jin Shu *Sichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Yingmin ZhouChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Xiangqian MengSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Guiquan ZhangChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Xinyu LvSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Guo LiChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Ping LeiSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Ming HeChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Zhen LeiSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Qian WangChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Lingli YiSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Liu YangChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.
Penghao LiSichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, China.
Bo LuoChina Conservation and Research Center for the Giant Panda, Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The advancement of artificial insemination techniques for giant pandas has significantly enhanced their breeding success. However, some pandas continue to experience difficulties in conceiving naturally, necessitating a thorough investigation into the underlying causes of infertility. This study aimed to perform pre-pregnancy examinations and diagnose infertility causes on giant pandas with infertility. Methods: A range of diagnostic methods, including behavioral observation, hormone assays, ultrasound imaging, laparoscopy, hysteroscopy, and colposcopy, were employed to conduct pre-pregnancy assessments and diagnose infertility in two giant pandas, designated as #A and #B. Results: Both pandas exhibited normal estrus behaviors, and their progesterone (P4) and estrone (E1G) levels during estrus paralleled those typically seen in successfully breeding individuals during estrus, remaining within the expected physiological range. Ultrasound evaluation of panda #A revealed a fluid accumulation surrounding the ovaries, with echogenicity noted along the walls of the adjacent fallopian tubes, suggesting the presence of hydrosalpinx, which was subsequently confirmed via laparoscopy. Hysteroscopic examination indicated that the vaginal and uterine structures of both pandas were normal. Conclusion: The estrous behaviors and hormonal profiles of the two infertile giant pandas were observed to be within normal ranges. The infertility in one of the subjects was attributed to the presence of hydrosalpinx.

Indexed as

B-ultrasoundcolposcopygiant pandahormonehysteroscopyinfertilitylaparoscopy

Identifiers

PMID42087997
PMCPMC13137947

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