Evidence map›Paper›PMID 42087898›Full record

ArticleCurrent developments in nutrition2026

The Effect of Including 1 Avocado Daily in a Habitual Diet on the Glycemic Index and Glycemic Load in Free-Living Adults with Overweight/Obesity.

Kristie LeBeau, Gina Segovia-Siapco, Celine Heskey, Abigail Clarke, Keiji Oda, Rawiwan Sirirat, Dulce Ruiz Rice, Joan Sabaté, Nirupa R Matthan, Cheryl H Gilhooly and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Current developments in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03528031 (Habitual Diet and Avocado Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03528031 nacompletednot on this map

Habitual Diet and Avocado Trial

TypeinterventionalSponsorWake Forest University Health SciencesRan2018 to 2020Enrolled1,008ConditionsIntra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides HighArmsIntervention Daily Avocado
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kristie LeBeauCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Gina Segovia-SiapcoCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Celine HeskeyCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Abigail ClarkeCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Keiji OdaCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Rawiwan SiriratCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Dulce Ruiz RiceCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Joan SabatéCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.
Nirupa R MatthanJean Mayer USDA Human Nutrition Center on Aging, Tufts University, Boston, MA, United States.
Cheryl H GilhoolyJean Mayer USDA Human Nutrition Center on Aging, Tufts University, Boston, MA, United States.
Kristina S PetersenDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, United States.
Penny Kris-EthertonDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, United States.
Zhaoping LiCenter for Human Nutrition, David Geffen School of Medicine at the University of California, Los Angeles, CA, United States.
David M ReboussinDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Sujatha RajaramCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Few studies have explored the effect of a single-food intervention on the dietary glycemic index (GI) and glycemic load (GL) within the context of a habitual diet. Avocados are low in carbohydrates but rich in monounsaturated fatty acids, fiber, and other bioactive compounds. This raises the question of whether eating 1 avocado a day could lower the GI and GL of the diet, potentially reducing cardiometabolic risk. Objectives: This study aimed to assess whether adding 1 large avocado (168 g) daily for 6 mo to the habitual diet of adults with abdominal obesity reduces dietary GI and/or GL. Methods: This secondary analysis used data from the Habitual Diet and Avocado Trial, a multicenter, randomized, parallel-arm study involving 1008 adults with elevated waist circumference. Participants were randomly assigned to either an avocado-supplemented group, instructed to consume 1 large avocado daily with their usual diet, or a control group who maintained their habitual diet and avoided avocados. Dietary intake was assessed via 3 unannounced 24-h dietary recalls over the 6-mo period, from which dietary GI and GL were calculated using Nutrition Data System for Research software. Linear regression models adjusted for age, sex, BMI, energy intake, race, ethnicity, education level, and study site were used to evaluate between-group differences. Results: Among 961 participants with complete data (73% females, mean age 50.5 y), the avocado-supplemented group showed a reduction in dietary GL by 13.7 points (95% confidence interval: 17.0, 10.4; Conclusions: Daily consumption of 1 avocado within the habitual diet significantly reduced GL by almost 14 points, without requiring significant dietary changes. This suggests that incorporating a single nutrient-dense food like avocado can effectively improve the GL simply and sustainably.This trial is registered at clinicaltrials.gov as NCT03528031.

Indexed as

abdominal obesityavocadocardiometabolic diseaseelevated waist circumferenceglycemic indexglycemic load

Identifiers

PMID42087898
PMCPMC13137022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.