Evidence map›Paper›PMID 42087888›Full record

ArticleProceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition2024

Improving EPI quality with GRAPPA in concurrent fMRI-fMRS at 7T.

Shahrokh Abbasi-Rad, Robert Frost, Nutandev Bikkamane Jayadev, Yulin Chang, Ovidiu Andronesi, David Norris, Zoe Kourtzi, Uzay Emir, André van der Kouwe

Abstract read
In one paragraph

Article in Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Stability of single-subject estimation of glutamate and GABA dynamics in concurrent fMRI-fMRS at 7 T.Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shahrokh Abbasi-RadAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Robert FrostAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
Nutandev Bikkamane JayadevSiemens Medical Solutions, Malvern, PA, United States.
Yulin ChangSiemens Medical Solutions, Malvern, PA, United States.
Ovidiu AndronesiAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.
David NorrisErwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany.
Zoe KourtziUniversity of Cambridge, Cambridge, United Kingdom.
Uzay EmirSchool of Health Sciences, Purdue University, West Lafayette, IN, United States.
André van der KouweAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States.

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Development of whole-brain in vivo 2HG imaging for precision medicine in mutant IDH gliomaR01CA211080 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Ovidiu C Andronesi · 2017 to 2026
$5.4M
Development of next generation 2HG and metabolic MR imaging for precision oncology of mutant IDH and wildtype glioma patientsR01CA255479 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI ANDRONESI, OVIDIU C · 2021 to 2025
$3.0M
Neuroimaging and gut microbiome markers of development in HIV-exposed uninfected infantsR01HD093578 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI HOLMES, MARTHA, KABA, MAMADOU · 2017 to 2022
$2.9M
Extension of a longitudinal cognitive and brain imaging study of early-treated perinatally HIV infected children through adolescenceR01HD099846 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LAUGHTON, BARBARA, MEINTJES, ERNESTA MARIA · 2019 to 2023
$2.7M
Neural correlates of in utero HIV and ART exposure: early childhood follow-up of a prospectively recruited cohortR01HD110152 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI Barbara Laughton, Ernesta Maria Meintjes · 2023 to 2026
$2.4M
Robust Precision Mapping of Cortical and Subcortical Brain Metabolic Signatures in ADR01AG079422 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LEE, PHIL, VAN DER KOUWE, ANDRE JAN WILLEM · 2023 to 2025
$2.4M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
Fetal Neuroprotection by choline supplementation in heavy drinking pregnant womenR01AA030014 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI ROBERT COLIN CARTER, SANDRA W. JACOBSON · 2023 to 2026
$1.9M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
Sequence-universal high-frequency prospective MRI motion correction with navigatorsR21EB029641 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI FROST, STEPHEN ROBERT · 2021 to 2023
$665k
Computeserver Structural &Functional Image AnalysisS10RR019307 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2004 to 2004
$496k
NCI NIH HHS R01 CA211080NCI NIH HHS R01 CA255479NCRR NIH HHS S10 RR019307NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NIAAA NIH HHS R01 AA030014NIA NIH HHS R01 AG079422NIBIB NIH HHS P41 EB015896NIBIB NIH HHS R21 EB029641NICHD NIH HHS R01 HD093578NICHD NIH HHS R01 HD099846NICHD NIH HHS R01 HD110152
6 · The paper itself

Abstract

Motivation: To develop a sequence for high-quality concurrent measurement of BOLD signal changes (fMRI) and biochemicals metabolite concentrations (fMRS). Goals: To implement parallel imaging with inline image reconstruction to improve fMRI image quality in concurrent fMRI-fMRS experiments at 7 T. Approach: We modified an fMRS-fMRI sequence to start by acquiring reference lines for GRAPPA reconstruction. Then each TR consists of a semiLASER acquisition for single-voxel MRS, and a GRAPPA-accelerated 3D EPI acquisition. Results: We obtained sufficient tSNR (30) map for the 3D EPI and a high SNR (59) and a narrow linewidth (9 Hz) for the spectrum. Impact: The modified concurrent fMRI-fMRS pulse sequence enhances the fMRI component to enable whole-brain coverage, reduced distortion, and high spatial resolution, providing a powerful tool for neuroscientists to study the dynamics of neurochemicals simultaneously with the BOLD signal.

Indexed as

BrainPulse Sequence Design

Identifiers

PMID42087888
PMCPMC13138720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.