ArticleEuropean journal of neurology2026
Functional Stroke Mimics: Patient Characteristics, CT-Based Multimodal Imaging and Long-Term Outcome in a Comparative Cohort Study.
Article in European journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
background and purposeFunctional stroke-like episodes (FSMs) are an increasingly recognised stroke mimic with demographic and clinical characteristics that differ from acute ischaemic strokes (AISs) but have unclear long-term outcomes. MATERIALS AND
methodsWe report retrospective data on consecutive patients with FSM who underwent acute perfusion-CT (PCT) admitted to Lausanne University Hospital (2003-2017). We compared them to all contemporaneous AISs undergoing PCT from the Acute-STroke-Registry-and-Analysis-of-Lausanne (ASTRAL).
resultsTwenty-five FSMs and 3201 control-AISs were included. FSM patients were significantly younger (median 43 vs. 73 years, adjusted odds ratio (OR
conclusionIn this single-centre cohort of consecutive FSMs undergoing acute PCT, we identified distinctive demographic and clinical features, normal CT-based neuroimaging, but still a high thrombolysis rate. Long-term observation revealed a high rate of recurrent functional events and persistent disability, suggesting the need for more effective treatment and regular follow-up.
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