ArticleMedical and veterinary entomology2026
Histopathological investigation of wound healing activities of Lucilia sericata Larva and Achillea sintenisii extract combinations in diabetic rat wound model.
Article in Medical and veterinary entomology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Histopathological investigation of wound healing activities of Lucilia sericata Larva and Achillea sintenisii extract combinations in diabetic rat wound model.Medical and veterinary entomology · 2026Article
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3 authors.
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Abstract
Chronic wounds, particularly in diabetic patients, represent a major clinical and economic burden on healthcare systems worldwide. Complementary therapies are increasingly integrated alongside conventional treatments to improve healing outcomes. Maggot debridement therapy (MDT), utilizing the larvae of Lucilia sericata, is a globally recognized method for treating non-healing wounds. These larvae secrete substances with antifungal, antibacterial and anti-inflammatory properties. Herbal remedies also play a role in chronic wound care, with various Achillea species traditionally used for medicinal purposes. This study investigated the wound healing effects of a pomade combining L. sericata larval secretions and Achillea sintenisii plant extract, compared to Furacin®, a commercial wound healing cream. Excisional wounds were created on diabetic Wistar albino rats, which were divided into four groups: DF (Furacin®), DM (L. sericata secretion), DA (A. sintenisii extract) and DM + DA (combined). Wound area, contraction rates and histological parameters were assessed at Days 0, 4, 8 and 12. Wound area decreased significantly across all groups over time (F = 511.9, p = 0.001), with mean values declining from 11.11 cm
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